| Tag | Content |
|---|
| CPLM ID | CPLM-017829 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Actin-related protein 8 |
Protein Synonyms/Alias | |
Gene Name | Actr8 |
Gene Synonyms/Alias | Arp8 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 225 | KYLEIPLKDLKYYRC | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity). |
Sequence Annotation | NP_BIND 283 286 ATP (By similarity).
BINDING 55 55 ATP (By similarity).
BINDING 56 56 ATP (By similarity).
MOD_RES 132 132 Phosphoserine (By similarity).
MOD_RES 412 412 Phosphoserine (By similarity). |
Keyword | ATP-binding; Cell cycle; Cell division; Chromosome; Complete proteome; DNA damage; DNA recombination; DNA repair; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 624 AA |
Protein Sequence | MTQAEKGDAE NGKEKGGEKE KEQRGVKRPI VPALVPESLQ EQIQSNFIVV IHPGSTTLRL 60
GRATDTLPVS VPHVIARRHK QQGQPLYKDN WLLREGLNKP ESNEQRQNGL KMVDQAIWSK 120
KMSNGTRRIP VSPEQTRSYN KQMRPAILDH CSGNKWTNTS QQPEYLVGEE ALYVNPLDCY 180
NIHWPIRRGQ LNIHPGPGGS LTAVLADIEV IWSHAIQKYL EIPLKDLKYY RCILLIPDIY 240
NKQHVKELVH MILMKMGFAG IVVHQESVCA TFGSGLSSTC VVDVGDQKTS VCCVEDGVSH 300
RNTRLCLAYG GSDVSRCFYW LMQRAGFPYR ECQLTNKMDC LLLQHLKETF CHLDQDISGL 360
QDHEFQIRHP DSPALLYQFR LGDEKLQAPM ALFYPATFGI VGQKMTTLQH RSQGDPEDPH 420
DEHYLLATQS KQEQSAKATA DRKSASKPIG FEGDLRGQSS DLPERLHSQE VDLASSQGDC 480
LMAGNESEEA LTALMSRKTA ISLFEGKALG LDKAILHSVD CCSSDDTKKK MYSSILVVGG 540
GLMFHKAQEF LQHRILNKMP PSFRRIIENV DVITRPKDMD PRLIAWKGGA VLACLDTTQE 600
LWIYQREWQR FGVRMLRERA AFVW 624 |
Gene Ontology | GO:0031011; C:Ino80 complex; IEA:Compara. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0051301; P:cell division; IEA:UniProtKB-KW. GO:0006310; P:DNA recombination; IEA:UniProtKB-KW. GO:0006281; P:DNA repair; IEA:UniProtKB-KW. GO:0007067; P:mitosis; IEA:UniProtKB-KW. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |