UniProt Accession

 UBC9_YEAST; P50623; D6VRT3 

Genbank Protein ID

 X82538; Z74112; BK006938 

Genbank Nucleotide ID

 CAA57888.1; CAA98629.1; DAA11793.1 

Protein Name

 SUMO-conjugating enzyme UBC9 

Protein Synonyms/Alias

 Ubiquitin carrier protein 9; Ubiquitin-conjugating enzyme E2-18 kDa; Ubiquitin-protein ligase 

Gene Name

 UBC9 

Gene Synonyms/Alias

 YDL064W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
27	HPFGFYAKPVKKADG	acetylation	[1]
153	KKVLLQAKQYSK***	sumoylation	[2]
157	LQAKQYSK*******	sumoylation	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] UBC9 autosumoylation negatively regulates sumoylation of septins in Saccharomyces cerevisiae.
 Ho CW, Chen HT, Hwang J.
 J Biol Chem. 2011 Jun 17;286(24):21826-34. [PMID: 21518767] 

Functional Description

 E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2). 

Sequence Annotation

 ACT_SITE 93 93 Glycyl thioester intermediate (By  

Keyword

 3D-structure; ATP-binding; Cell cycle; Cell division; Complete proteome; Ligase; Mitosis; Nucleotide-binding; Nucleus; Reference proteome; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 157 AA 

Protein Sequence

Gene Ontology

 GO:0000794; C:condensed nuclear chromosome; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019789; F:SUMO ligase activity; IDA:SGD.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0000022; P:mitotic spindle elongation; IMP:SGD.
 GO:0016925; P:protein sumoylation; IDA:SGD. 

Interpro

 IPR027230; Ubc9.
 IPR000608; UBQ-conjugat_E2.
 IPR023313; UBQ-conjugating_AS.
 IPR016135; UBQ-conjugating_enzyme/RWD. 

Pfam

 PF00179; UQ_con 

SMART

  

PROSITE

 PS00183; UBIQUITIN_CONJUGAT_1
 PS50127; UBIQUITIN_CONJUGAT_2 

PRINTS