CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035577
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Periplakin (Predicted) 
Protein Synonyms/Alias
 Protein Ppl 
Gene Name
 Ppl 
Gene Synonyms/Alias
 Ppl_predicted; rCG_49866 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
12FRKKNKGKYSPTVQTacetylation[1]
36DLIEQLQKNADQVERacetylation[1]
93EADSAIAKHMKHPQGubiquitination[2]
145WDALVDEKLDKLSSQacetylation[1]
184AIGPHLAKDKEQNSEacetylation[1]
186GPHLAKDKEQNSELQacetylation[1]
264INRNLEAKEERINKLacetylation[1]
325EDYHQFHKDMKDAQEacetylation[1]
328HQFHKDMKDAQELLRacetylation[1]
367RELDDQEKALDKYEDacetylation[1]
371DQEKALDKYEDVVRGacetylation[1]
608LLEAAQEKVDVANRLacetylation[1]
805DYELEAEKLRSLLDLacetylation[1]
895EETWKIQKELEEEMEubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1754 AA 
Protein Sequence
MHSLFRKKNK GKYSPTVQTR SISNKELSDL IEQLQKNADQ VERNIVDTEA KMQSDLARMQ 60
DGQLPEHRDA TLQNVSDSEK LLYVLEADSA IAKHMKHPQG DMIAEDIRQL KERVTNLRGK 120
HKQMYSLAVR EADPKVNWDA LVDEKLDKLS SQSFGTDLPL VDSQVEQHNI FHNEVKAIGP 180
HLAKDKEQNS ELQAKYQKLL AASQARQQHL SSLQDYMQRC TNELYWLDQQ AKGRIQYDWS 240
DRNLDYPSRR RQYENFINRN LEAKEERINK LHTEGDQLLT AEHPGRNSIE AHMEAVHAEW 300
KEYLNLLICE ESHLKYMEDY HQFHKDMKDA QELLRKVDSD LNQKYSPDFK DRYQIELLLR 360
ELDDQEKALD KYEDVVRGLQ KRGQQVLPLK YRRETPLKPI PVEALCDFEG DQGLISRGYS 420
YTLQKNNGES WELTDSTGKK LMAPAVCFII PPTDPEALAL SDSLGSQYRS VRQKAAGSKH 480
ALQQRHEVLR TENPGDASDL QGRQLLAGLD QVASDLDRQE KAITGILRPP LEQGRAIEDS 540
AERAKHLKNI TNELLQIEPE KIQRTAECEA FVQALPGSGT TPLLKTRVED TNQKYKRLVQ 600
LLEAAQEKVD VANRLENSLQ RGRELLASHE NRLMQDDTIP ESDYMLDSKR QELEAMASEL 660
QAQKSLLGEV EQNLQVAKQC SSSLASRFQE HCPDLERQEA EVHKLNQRFN NLNQQVERRA 720
QSLQSARDAY SEYCRGYDHV LQFLVKTPSY EPQETDSLSQ METKLKNQKN LLDEIASMEQ 780
GAQKVYADSQ QYQQAVKDYE LEAEKLRSLL DLENGRNSHV NKRARLQSPA AKVKEEEAAL 840
AAKFTEVNAI NRQRLQNLEF ALNLLRQQPE AGVTHETLQG REQGSGMEET WKIQKELEEE 900
MERRQQLENE VKSAQEEIQT LKDQGPQESL VRKEVLKKVP DPALEESFQQ LQQTLAEEQH 960
KNQLLQEELG ALQLRLQALE QETRDGGQEY VVKEVLRIEP DRAQEDEVLQ LREELEGLRR 1020
QKGAREAEVL LLQQRVAALA AEKSRVQEKV TEREVVKLQN DPQLEAEYRR LQEEHQREGT 1080
LREKQEEELS FLQAKLRRLE KERAMAEGKI TVKEVLKVEK DTAAEREVND LSRQYEDEAS 1140
KARTSQREKT ELLRKIWALE EENAKVVVQE KVREIVRPDP KAESEVANLR LELVEQERKF 1200
RGAEEQLKSY QSELEALRNR GPQVEVKEVT KEVIKYTTDP ETEQELQRLR EEIMDKTRLI 1260
ERCDLEIYQL KQEIQILKDT KPQVQTREVV QEILQFQEDP QTKKEVESLR IQLSEEKKKL 1320
VDLEGEQASQ EEKIKRKEEE LAQGKERIVR QEVVQYEDEP DLRAEVTAFT DSIDVELRQI 1380
DKLCVELRRL QHRRAELERQ LEELERERQA RRAAELEVQR LQQRLAALEQ EEAKTGEKVT 1440
HTQKVVLQQD PQQTREHALL RAQLEEERHR RQLLEGELEP LRRKLAALEK TEIKEKVVFS 1500
ESVQVEKGDT EQEIQRLKKS LEEESRSKRE LDSEVTRLEA KLSELEFYNS KSSKELDFLR 1560
EENHKLQLER QNLQLETRRL QSEIEMAATE TRDLKNITMV DSGTHLNSRL WSLEKELDDL 1620
KKMSKDKDLE IDELQRRLGS VAVKREQREN HLRRSIVVID PDTGRELSPE EAHRAGLIDW 1680
KMFVKLRSQE CDWEEISVKG PNGESSVIHD RKSGKKFSIE DALQSGRLTP AQYDRYVNKD 1740
MSIQELAVLV SGQK 1754 
Gene Ontology
 GO:0005856; C:cytoskeleton; IEA:InterPro. 
Interpro
 IPR001101; Plectin_repeat.
 IPR018159; Spectrin/alpha-actinin. 
Pfam
 PF00681; Plectin 
SMART
 SM00250; PLEC
 SM00150; SPEC 
PROSITE
  
PRINTS