CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001478
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein transport protein Sec24D 
Protein Synonyms/Alias
 SEC24-related protein D 
Gene Name
 SEC24D 
Gene Synonyms/Alias
 KIAA0755 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
339IPLAAVIKPFATIPSubiquitination[1]
577KAADCPGKLFIFHSSubiquitination[1]
595AEAPGKLKNRDDKKLubiquitination[1]
685LRNDIEKKIGFDAIMubiquitination[1]
792ALINFFAKSAFKAVLubiquitination[1]
804AVLHQPLKVIREILVubiquitination[1]
852VYMNCLLKNCVLLSRubiquitination[1]
981IMGIIQQKRPYSMKLubiquitination[1]
992SMKLTIVKQREQPEMubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. 
Sequence Annotation
 REGION 363 388 Zinc finger-like.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Polymorphism; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1032 AA 
Protein Sequence
MSQQGYVATP PYSQPQPGIG LSPPHYGHYG DPSHTASPTG MMKPAGPLGA TATRGMLPPG 60
PPPPGPHQFG QNGAHATGHP PQRFPGPPPV NNVASSHAPY QPSAQSSYPG PISTSSVTQL 120
GSQLSAMQIN SYGSGMAPPS QGPPGPLSAT SLQTPPRPPQ PSILQPGSQV LPPPPTTLNG 180
PGASPLPLPM YRPDGLSGPP PPNAQYQPPP LPGQTLGAGY PPQQAANSGP QMAGAQLSYP 240
GGFPGGPAQM AGPPQPQKKL DPDSIPSPIQ VIENDRASRG GQVYATNTRG QIPPLVTTDC 300
MIQDQGNASP RFIRCTTYCF PCTSDMAKQA QIPLAAVIKP FATIPSNESP LYLVNHGESG 360
PVRCNRCKAY MCPFMQFIEG GRRYQCGFCN CVNDVPPFYF QHLDHIGRRL DHYEKPELSL 420
GSYEYVATLD YCRKSKPPNP PAFIFMIDVS YSNIKNGLVK LICEELKTML EKIPKEEQEE 480
TSAIRVGFIT YNKVLHFFNV KSNLAQPQMM VVTDVGEVFV PLLDGFLVNY QESQSVIHNL 540
LDQIPDMFAD SNENETVFAP VIQAGMEALK AADCPGKLFI FHSSLPTAEA PGKLKNRDDK 600
KLVNTDKEKI LFQPQTNVYD SLAKDCVAHG CSVTLFLFPS QYVDVASLGL VPQLTGGTLY 660
KYNNFQMHLD RQQFLNDLRN DIEKKIGFDA IMRVRTSTGF RATDFFGGIL MNNTTDVEMA 720
AIDCDKAVTV EFKHDDKLSE DSGALIQCAV LYTTISGQRR LRIHNLGLNC SSQLADLYKS 780
CETDALINFF AKSAFKAVLH QPLKVIREIL VNQTAHMLAC YRKNCASPSA ASQLILPDSM 840
KVLPVYMNCL LKNCVLLSRP EISTDERAYQ RQLVMTMGVA DSQLFFYPQL LPIHTLDVKS 900
TMLPAAVRCS ESRLSEEGIF LLANGLHMFL WLGVSSPPEL IQGIFNVPSF AHINTDMTLL 960
PEVGNPYSQQ LRMIMGIIQQ KRPYSMKLTI VKQREQPEMV FRQFLVEDKG LYGGSSYVDF 1020
LCCVHKEICQ LLN 1033 
Gene Ontology
 GO:0030127; C:COPII vesicle coat; NAS:UniProtKB.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
 GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
 GO:0048208; P:COPII vesicle coating; TAS:Reactome.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0043687; P:post-translational protein modification; TAS:Reactome.
 GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
 GO:0044281; P:small molecule metabolic process; TAS:Reactome. 
Interpro
 IPR007123; Gelsolin_dom.
 IPR006900; Sec23/24_helical_dom.
 IPR006896; Sec23/24_trunk_dom.
 IPR012990; Sec23_24_beta_S.
 IPR002035; VWF_A.
 IPR006895; Znf_Sec23_Sec24. 
Pfam
 PF00626; Gelsolin
 PF08033; Sec23_BS
 PF04815; Sec23_helical
 PF04811; Sec23_trunk
 PF04810; zf-Sec23_Sec24 
SMART
  
PROSITE
  
PRINTS