CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035270
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Regulator of G-protein-signaling 7 
Protein Synonyms/Alias
  
Gene Name
 Rgs7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
5***MQDEKNGIPIRTacetylation[1]
192SRMRNPHKTRKSVYGubiquitination[2]
395DAQEHIYKLMKSDSYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 444 AA 
Protein Sequence
MQDEKNGIPI RTVKSFLSKI PSVFSGSDIV QWLIKNLTIE DPVEALHLGT LMAAHGYFFP 60
ISDHVLTLKD DGTFYRFQTP YFWPSNCWEP ENTDYAVYLC KRTMQNKARL ELADYEAESL 120
ARLQRAFARK WEFIFMQAEA QAKVDKKRDK IERKILDSQE RAFWDVHRPV PGCVNTTEVD 180
IKKSSRMRNP HKTRKSVYGL QNDIRSHSPT HTPTPETKPP TEDELHRQIK YWQIQLDRHR 240
LKMSKVADSL LSYTEQYVEY DPFLVPPDPS NPWLSDDTTF WELEASKEPS QQRVKRWGFG 300
MDEALKDPVG REQFLKFLES EFSSENLRFW LAVEDLKKRP IREVPSRVQE IWQEFLAPGA 360
PSAINLDSKS YDKTTQNVKE PGRYTFEDAQ EHIYKLMKSD SYPRFIRSSA YQELLQAKRK 420
GRNIPIFPCH KNCTPTLRAS TNLL 444 
Gene Ontology
 GO:0044292; C:dendrite terminus; IEA:Compara.
 GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0004871; F:signal transducer activity; IEA:InterPro.
 GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000591; DEP_dom.
 IPR015898; G-protein_gamma-like_dom.
 IPR000342; Regulat_G_prot_signal.
 IPR024066; Regulat_G_prot_signal_dom1.
 IPR016137; Regulat_G_prot_signal_superfam.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00610; DEP
 PF00631; G-gamma
 PF00615; RGS 
SMART
 SM00049; DEP
 SM00224; GGL
 SM00315; RGS 
PROSITE
 PS50186; DEP
 PS50132; RGS 
PRINTS
 PR01301; RGSPROTEIN.