CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001396
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein bassoon 
Protein Synonyms/Alias
  
Gene Name
 Bsn 
Gene Synonyms/Alias
 Kiaa0434 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
890LAKHSAQKASARPRPacetylation[1]
890LAKHSAQKASARPRPsuccinylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses (By similarity). Involved in the formation of the retinal photoreceptor ribbon synapses. 
Sequence Annotation
 REPEAT 570 576 1.
 REPEAT 577 583 2.
 REPEAT 584 590 3.
 REPEAT 591 597 4.
 REPEAT 598 604 5.
 ZN_FING 167 190 C4-type (Potential).
 ZN_FING 195 217 C4-type (Potential).
 ZN_FING 464 487 C4-type (Potential).
 ZN_FING 492 514 C4-type (Potential).
 REGION 62 71 5 X 2 AA tandem repeats of P-G.
 REGION 570 604 5 X 7 AA tandem repeats of K-A-S-P-Q-
 MOD_RES 6 6 Phosphoserine.
 MOD_RES 105 105 Phosphoserine.
 MOD_RES 142 142 Phosphoserine.
 MOD_RES 980 980 Phosphoserine.
 MOD_RES 1019 1019 Phosphoserine.
 MOD_RES 1102 1102 Phosphothreonine.
 MOD_RES 1105 1105 Phosphoserine.
 MOD_RES 1108 1108 Phosphoserine.
 MOD_RES 1114 1114 Phosphoserine.
 MOD_RES 1116 1116 Phosphothreonine.
 MOD_RES 1136 1136 Phosphotyrosine.
 MOD_RES 1236 1236 Phosphoserine.
 MOD_RES 1406 1406 Phosphothreonine.
 MOD_RES 1481 1481 Phosphoserine.
 MOD_RES 1482 1482 Phosphoserine.
 MOD_RES 1486 1486 Phosphoserine.
 MOD_RES 1493 1493 Phosphoserine.
 MOD_RES 1495 1495 Phosphothreonine.
 MOD_RES 1497 1497 Phosphoserine.
 MOD_RES 1510 1510 Phosphoserine.
 MOD_RES 1553 1553 Phosphoserine.
 MOD_RES 1554 1554 Phosphoserine.
 MOD_RES 2029 2029 Phosphoserine.
 MOD_RES 2044 2044 Phosphotyrosine.
 MOD_RES 2073 2073 Phosphotyrosine.
 MOD_RES 2122 2122 Phosphoserine.
 MOD_RES 2124 2124 Phosphoserine.
 MOD_RES 2578 2578 Phosphoserine.
 MOD_RES 2595 2595 Phosphothreonine.
 MOD_RES 2622 2622 Phosphothreonine.
 MOD_RES 2694 2694 Phosphoserine.
 MOD_RES 2703 2703 Phosphothreonine.
 MOD_RES 2808 2808 Phosphoserine.
 MOD_RES 2811 2811 Phosphoserine.
 MOD_RES 2822 2822 Phosphoserine.
 MOD_RES 2858 2858 Phosphoserine.
 MOD_RES 2860 2860 Phosphoserine.
 MOD_RES 2866 2866 Phosphoserine.
 MOD_RES 2908 2908 Phosphoserine.
 MOD_RES 3022 3022 Phosphoserine.
 MOD_RES 3301 3301 Phosphoserine.
 MOD_RES 3382 3382 Phosphoserine.
 MOD_RES 3431 3431 Phosphotyrosine.
 MOD_RES 3432 3432 Phosphotyrosine.
 MOD_RES 3459 3459 Phosphotyrosine.
 LIPID 2 2 N-myristoyl glycine (By similarity).
 CARBOHYD 1354 1354 O-linked (GlcNAc) (By similarity).
 CARBOHYD 1395 1395 O-linked (GlcNAc).
 CARBOHYD 1707 1707 O-linked (GlcNAc).
 CARBOHYD 1934 1934 O-linked (GlcNAc).
 CARBOHYD 2318 2318 O-linked (GlcNAc).
 CARBOHYD 2524 2524 O-linked (GlcNAc).
 CARBOHYD 2700 2700 O-linked (GlcNAc).
 CARBOHYD 2945 2945 O-linked (GlcNAc).  
Keyword
 Alternative splicing; Cell junction; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Glycoprotein; Lipoprotein; Metal-binding; Myristate; Phosphoprotein; Reference proteome; Repeat; Synapse; Synaptosome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3942 AA 
Protein Sequence
MGNEASLEGG AGEGPLPPGG SGLGPGPGAG KPPSALAGGG QLPVAGAARA AGPPTPGLGP 60
VPGPGPGPGP GSVPRRLDPK EPLGSQRTTS PTPKQASATA PGRESPRETR AQGPSGQEAE 120
SPRRTLQVDS RTQRSGRSPS VSPDRGSTPT SPYSVPQIAP LPSSTLCPIC KTSDLTSTPS 180
QPNFNTCTQC HNKVCNQCGF NPNPHLTQVK EWLCLNCQMQ RALGMDMTTA PRSKSQQQLH 240
SPALSPAHSP AKQPLGKPEQ ERSPRGPGAT QSGPRQAEAA RATSVPGPTQ ATAPPEVGRV 300
SPQPPLSTKP STAEPRPPAG EAQGKSATTV PSGLGAGEQT QEGLTGKLFG LGASLLTQAS 360
TLMSVQPEAD TQGQPSPSKG QPKIVFSDAS KEAGPRPPGS GPGPGPTPGA KTEPGARMGP 420
GSGPGALAKT GGTASPKHGR AEHQAASKAA AKPKTMPKER ASACPLCQAE LNMGSRGPAN 480
YNTCTACKLQ VCNLCGFNPT PHLVEKTEWL CLNCQTKRLL EGSLGEPAPL PLPTPQQPPA 540
GVPHRAAGAA PLKQKGPQGL GQPSGSLPAK ASPQATKASP QATKASPQAT KASPQTTKAS 600
PQAKPLRATE PSKTSSSAQE KKTVTSAKAE PVPKPPPETT VPPGTPKAKS GVKRTDPATP 660
VVKPVPEAPK GGEAEEPVPK PYSQDLSRSP QSLSDTGYSS DGVSSSQSEI TGVVQQEVEQ 720
LDSAGVTGPR PPSPSELHKV GSSLRPSLEA QAVAPSAEWS KPPRSSSSAV EDQKRRPHSL 780
SITPEAFDSD EELGDILEED DSLAWGRQRE QQDTAESSDD FGSQLRHDYV EDSSEGGLSP 840
LPPQPPARAD MTDEEFMRRQ ILEMSAEEDN LEEDDTAVSG RGLAKHSAQK ASARPRPESS 900
QEPKRRLPHN ATTGYEELLS EAGPAEPTDS SGALQGGLRR FKTIELNSTG SYGHELDLGQ 960
GPDPNLDREP ELEMESLTGS PEDRSRGEHS STLPASTPSY TSGTSPTSLS SLEEDSDSSP 1020
SRRQRLEEAK QQRKARHRSH GPLLPTIEDS SEEEELREEE ELLREQEKMR EVEQQRIRST 1080
ARKTRRDKEE LRAQRRRERS KTPPSNLSPI EDASPTEELR QAAEMEELHR SSCSEYSPSP 1140
SLDSEAETLD GGPTRLYKSG SEYNLPAFMS LYSPTETPSG SSTTPSSGRP LKSAEEAYED 1200
MMRKAEMLQR QQGQVAGARG PHGGPSQPTG PRSQGSFEYQ DTQDHDYGGR ASQPVAESTP 1260
AGLGAAVYEE ILQTSQSIAR MRQASSRDLG FTEDKKKEKQ FLNAESAYMD PMKQNGGPLT 1320
PGTSPTQLAA PVSFSTSTSS DSSGGRVIPD VRVTQHFAKE PQDPLKLHSS PVSSTLTSKE 1380
VGMTFSQGPG SPATTASPTR GYMTPTSPAG SERSPSTSST IHSYGQPPTT ANYGSQTEEL 1440
PHAPSGPPGS GRAPREKPLS GGDSEVGAPQ PSRGYSYFTG SSPPLSPSTP SESPTFSPGK 1500
LGPRATAEFS TQTPSLTLSS DIPRSPGPPS PMVAQGTQTP HRPSTPRLVW QQSSQEAPIM 1560
VITLASDASS QTRMVHASAS TSPLCSPTDS QPTSHSYSQT TPPSASQMPS EPAGPPGFPR 1620
APSAGTDGPL ALYGWGALPA ENISLCRISS VPGTSRVEPG PRPPGTAVVD LRTAVKPTPI 1680
ILTDQGMDLT SLAVEARKYG LALDPVSGRQ STAVQPLVIN LNAQEQTHTF LATATTVSIT 1740
MASSVLMAQQ KQPVVYGDPF QSRLDFGQGS GSPVCLAQVK QVEQAVQTAP YRGGPRGRPR 1800
EAKFARYNLP NQVTPLARRD ILITQMGTAQ GVGLKPGPVP EPGAEPHRAT PAELRSHAPP 1860
GTRKPHTVVV QMGEGTAGTV TTLLPEEPAG ALDLTGMRPE SQLACCDMVY KFPFGSSCTG 1920
TFHPAPSAPD KSVTDTALPG QSSGPFYSPR DPEPPEPLTF RTQGVVGPGP HEEQRPYPQG 1980
LPGRLYSSMS DTNLAEAGLN YHAQRLGQLF QGPGRDSAVD LSSLKHSYSL GFADGRYLGQ 2040
GLQYGSFTDL RHPTDLLSHP LPLRRYSSVS NIYSDHRYGP RGDAVGFQEA SLAQYSATTA 2100
REISRMCAAL NSMDQYGGRH GSGSGGPDLV QYQPQHGPGL SAPQGLAPLR SGLLGNPTYP 2160
EGQPSPGNLA QYGPAASQAT AVRQLLPSTA TVRAADGMIY STINTPIAAT LPITTQPASV 2220
LRPMVRGGMY RPYVSGGVTA VPLTSLTRVP MIAPRVPLGP AGLYRYPAPR FPIASSVPPA 2280
EGPVYLGKPA AAKASGAGGP PRPELPAGVA REEPFSTTAP AVIKEAPVAP APGPAPAPPP 2340
GQKPAGEAVA GSGSGVLSRP ASEKEEASQE DRQRKQQEQL LQLERERVEL EKLRQLRLQE 2400
ELERERVELQ RHREEEQLLV QRELQELQTI KQHVLQQQQE ERQAQFALQR EQLAQQRLQL 2460
EQIQQLQQQL QLQLEEQKQR QKAPFPATCE APSRGPPPAA TELAQNGQYW PPLTHAAFIA 2520
VAGTEGPGQP REPVLHRGLP SSASDMSLQT EEQWEAGRSG IKKRHSMPRL RDACEPESGP 2580
DPSTVRRIAD SSVQTDDEEG EGRYLVTRRR RTRRSADCSV QTDDEDNADW EQPVRRRRSR 2640
LSRHSDSGSD SKHDATASSS TTAAATARAM SSVGIQTISD CSVQTEPEQL PRVSPAIHIT 2700
AATDPKVEIV RYISAPEKTG RGESLACQTE PDGQAQGVAG PQLIGPTAIS PYLPGIQIVT 2760
PGALGRFEKK KPDPLEIGYQ AHLPPESLSQ LVSRQPPKSP QVLYSPVSPL SPHRLLDTSF 2820
ASSERLNKAH VSPQKQFIAD STLRQQTLPR PMKTLQRSLS DPKPLSPTAE ESAKERFSLY 2880
QHQGGLGSQV SALPPNGLVR KVKRTLPSPP PEEAHLPLAG QVPSQLYAAS LLQRGLAGPT 2940
TVPATKASLL RELDRDLRLV EHESTKLRKK QAELDEEEKE IDAKLKYLEL GITQRKESLA 3000
KDRGGRDYPP LRGLGEHRDY LSDSELNQLR LQGCTTPAGQ YVDYPASAAV PATPSGPTAF 3060
QQPRFPPAAP QYTAGSSGPT QNGFPAHQAP TYTGPSTYPA PTYPPGTGYP AEPGLPSQPA 3120
FHPTGHYAAP TPMPTTQSAP FPVQADSRAA HQKPRQTSLA DLEQKVPTNY EVIGSPAVTM 3180
SSAPPETGYS GPAVSGSYEQ GKAPEHPRGS DRSSVSQSPA PTYPSDSHYT SLEQNVPRNY 3240
VMIDDISELT KDSTPTASES QRLEPLGPGG VSGRPGKDPG EPAVLEGPTL PCCYGRGEEE 3300
SEEDSYDPRG KSGHHRSMES NGRPSTHYYG DSDYRHGARA DKYGPGPMGP KHPSKSLAPA 3360
AISSKRSKHR KQGMEQKISK FSPIEEAKDV ESDLASYPPP TVSSSLTSRG RKFQDEITYG 3420
LKKNVYEQQR YYGVSSRDAA EEDERMYGSS SRSRMASAYS GEKLSSHDYS SRGKGYERER 3480
DTAERLQKAG SKPSSLSMAH GRARPPMRSQ ASEEESPVSP LGRPRPAGGA LPPGDTCPQF 3540
CSSHSMPDVQ EHVKDGPRAH AYKREEGYML DDSHCVVSDS EAYHLGQEET DWFDKPRDAR 3600
SDRFRHHGGH TVSSSQKRGP ARHSYHDYDE PPEEGLWPHD EGGPGRHTSA KEHRHHSDHG 3660
RHSGRHAGEE PGRRAAKPHA RDMGRHEARP HPQASPAPAM QKKGQPGYPS SADYSQSSRA 3720
PSAYHHASES KKGSRQAHTG PSALQPKADT QAQPQMQGRQ AAPGPQQSQP PSSRQTPSGT 3780
ASRQPQTQQQ QQQQQQQQGL GQQAPQQAPS QARLQPQSQP TTRGTAPAAS QPAGKPQPGP 3840
TTAPGPQPAG PPRAEQASSS KPPAAKAPQQ GRAPQAQTTP GPGPAGAKPG ARPGGTPGAP 3900
ASQPGAEGES VFSKILPGGA AEQAGKLTEA VSAFGKKFSS FW 3942 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0030425; C:dendrite; IDA:BHF-UCL.
 GO:0019898; C:extrinsic to membrane; ISO:MGI.
 GO:0015630; C:microtubule cytoskeleton; IEA:Compara.
 GO:0044306; C:neuron projection terminus; IDA:MGI.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048786; C:presynaptic active zone; IDA:MGI.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR011011; Znf_FYVE_PHD.
 IPR008899; Znf_piccolo.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF05715; zf-piccolo 
SMART
  
PROSITE
  
PRINTS