CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035100
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
359PVGVHPKKLDEAVAEacetylation[1]
378KQNVKLTKLTEKQAQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 BINDING 57 57 Substrate (By similarity).
 BINDING 129 129 Substrate (By similarity).
 BINDING 154 154 Substrate (By similarity).
 BINDING 184 184 Substrate (By similarity).
 BINDING 188 188 Substrate (By similarity).  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 402 AA 
Protein Sequence
MSDKLPYRVS DFGLAAWEQK ALEVAENEMP GLMCMREMNS VSKPLKGAHI ASCLHVTVET 60
AVLIETLVAL GAEVRCSSCN IFSTQDHAVA AIAKAGVPVF AERARQISST WGALCRCCTL 120
RMFNMILDDG GDLTNLIYTK YPQLLSGTRG ISEETMSGAH NLYKMMANEI LKVPAINVND 180
SVAKNKFDNL YGCRESLVDG IKQATDVMVS GKVAALAGYG DVGGCAQALR GFGARVIIAE 240
TPINALQTSK VTTMGDACKE GNIFVTTTGC VDIVFGLHFE QMKDDAIVWL NENAVHMVNI 300
KSQVGHYWLK SRHCIILLAE GHLVNLPFMM SNSFTSQVVA QIELWTHPDK YPVGVHPKKL 360
DEAVAEAHLG KQNVKLTKLT EKQAQYLGMP VNSPFKPEHY RY 402 
Gene Ontology
 GO:0004013; F:adenosylhomocysteinase activity; IEA:InterPro.
 GO:0006730; P:one-carbon metabolic process; IEA:InterPro. 
Interpro
 IPR000043; Adenosylhomocysteinase.
 IPR015878; Ado_hCys_hydrolase_NAD-bd.
 IPR016040; NAD(P)-bd_dom.
 IPR020082; S-Ado-L-homoCys_hydrolase_CS. 
Pfam
 PF05221; AdoHcyase
 PF00670; AdoHcyase_NAD 
SMART
 SM00996; AdoHcyase
 SM00997; AdoHcyase_NAD 
PROSITE
 PS00738; ADOHCYASE_1 
PRINTS