CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024336
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Anoctamin-3 
Protein Synonyms/Alias
 Transmembrane protein 16C 
Gene Name
 Ano3 
Gene Synonyms/Alias
 Tmem16c 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
110CLALGKDKDYLDESEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). 
Sequence Annotation
 CARBOHYD 425 425 N-linked (GlcNAc...) (Potential).
 CARBOHYD 448 448 N-linked (GlcNAc...) (Potential).
 CARBOHYD 455 455 N-linked (GlcNAc...) (Potential).
 CARBOHYD 866 866 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 981 AA 
Protein Sequence
MVHHSGSIQS FKQQKGMNIS KSEITTEASL KPSRRSLPCL AQSYAHSKSL SQSASLFQST 60
ESESQAPTSV TFLSADKPEH VTSEESRKDS TLKCSFADLS DFCLALGKDK DYLDESEHAN 120
YDRSRLLNDF VTKDKPASKT KLSKNDMSYI ASSGLLFKDG KKRIDYILVY RKTNIQYDKR 180
NTFEKNLRAE GLMLEKEPAI ANPDIMFIKI HIPWDTLCKY AERLNIRVPF RKKCYYTDQK 240
NKSKSRVQNY FKRIKKWMSQ NPMVLDKSAF PELEESDCYT GPFSRARIHH FIINNKDTFF 300
SNATRSRIVY HMLERTKYEN GISKVGIRKL ITNGSYIAAF PPHEGAYKSS LPIKTHGPQN 360
NRHLLYERWA RWGMWYKHQP LDLIRMYFGE KIGLYFAWLG WYTGMLIPAA VVGLCVFFYG 420
LVTMNESQVS QEICKATEVF MCPLCDKNCS LQRLNDSCIY AKVTYLFDNG GTVFFAIFMA 480
IWATVFLEFW KRRRSILTYT WDLIEWEEEE ETLRPQFEAK YYRMEVINPI TGKPEPHQPS 540
SDKVTRLLVS VSGIFFMISL VITAVFAVVV YRLVVMEQFA SFKWNFVKQH WQFATSGAAV 600
CINFIIIMLL NLAYEKIAYL LTNLEYPRTE SEWENSFALK MFLFQFVNLN SSIFYIAFFL 660
GRFVGHPGKY NKLFERWRLE ECHPSGCLID LCLQMGVIMF LKQIWNNFME LGYPLIQNWW 720
SRHKIKRGIQ DASIPQWEND WNLQPMNIHG LMDEYLEMVL QFGFTTIFVA AFPLAPLLAL 780
LNNIIEIRLD AYKFVTQWRR PLPARATDIG IWLGILEGIG ILAVITNAFV IAITSDYIPR 840
FVYEYKYGPC ANHVKQNENC LKGYVNNSLS FFDLSELGMG KSGYCRYRDY RGPPWSSKPY 900
EFTLQYWHIL AARLAFIIVF EHLVFGIKSF IAYLIPDIPK GLRERIRREK YLVQEMMYEA 960
ELEHLQQQRR KSGQPIHHEW P 981 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. 
Interpro
 IPR007632; Anoctamin. 
Pfam
 PF04547; Anoctamin 
SMART
  
PROSITE
  
PRINTS