CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003238
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 D-serine/D-alanine/glycine transporter 
Protein Synonyms/Alias
  
Gene Name
 cycA 
Gene Synonyms/Alias
 dagA; ytfD; b4208; JW4166 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
6**MVDQVKVVADDQAacetylation[1]
243AETKDPEKSLPRAINacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Permease that is involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine. 
Sequence Annotation
  
Keyword
 Amino-acid transport; Cell inner membrane; Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 470 AA 
Protein Sequence
MVDQVKVVAD DQAPAEQSLR RNLTNRHIQL IAIGGAIGTG LFMGSGKTIS LAGPSIIFVY 60
MIIGFMLFFV MRAMGELLLS NLEYKSFSDF ASDLLGPWAG YFTGWTYWFC WVVTGMADVV 120
AITAYAQFWF PDLSDWVASL AVIVLLLTLN LATVKMFGEM EFWFAMIKIV AIVSLIVVGL 180
VMVAMHFQSP TGVEASFAHL WNDGGWFPKG LSGFFAGFQI AVFAFVGIEL VGTTAAETKD 240
PEKSLPRAIN SIPIRIIMFY VFALIVIMSV TPWSSVVPEK SPFVELFVLV GLPAAASVIN 300
FVVLTSAASS ANSGVFSTSR MLFGLAQEGV APKAFAKLSK RAVPAKGLTF SCICLLGGVV 360
MLYVNPSVIG AFTMITTVSA ILFMFVWTII LCSYLVYRKQ RPHLHEKSIY KMPLGKLMCW 420
VCMAFFVFVV VLLTLEDDTR QALLVTPLWF IALGLGWLFI GKKRAAELRK 470 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0042895; F:antibiotic transporter activity; IMP:EcoCyc.
 GO:0001761; F:beta-alanine transmembrane transporter activity; IMP:EcoCyc.
 GO:0042944; F:D-alanine transmembrane transporter activity; IMP:EcoCyc.
 GO:0042945; F:D-serine transmembrane transporter activity; IMP:EcoCyc.
 GO:0015187; F:glycine transmembrane transporter activity; IMP:EcoCyc.
 GO:0015180; F:L-alanine transmembrane transporter activity; IMP:EcoCyc. 
Interpro
 IPR004841; AA-permease_dom.
 IPR002293; AA/rel_permease1.
 IPR004840; Amoino_acid_permease_CS. 
Pfam
 PF00324; AA_permease 
SMART
  
PROSITE
 PS00218; AMINO_ACID_PERMEASE_1 
PRINTS