CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008242
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SVP1-like protein 2 
Protein Synonyms/Alias
  
Gene Name
 HSV2 
Gene Synonyms/Alias
 YGR223C; G8530 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
50NTDPLTSKLSKTFKEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Involved in piecemeal microautophagy of the nucleus (micronucleophagy). 
Sequence Annotation
 REPEAT 222 262 WD 1.
 REPEAT 267 306 WD 2.
 CARBOHYD 61 61 N-linked (GlcNAc...) (Potential).
 CARBOHYD 155 155 N-linked (GlcNAc...) (Potential).
 CARBOHYD 256 256 N-linked (GlcNAc...) (Potential).
 CARBOHYD 280 280 N-linked (GlcNAc...) (Potential).
 CARBOHYD 315 315 N-linked (GlcNAc...) (Potential).
 CARBOHYD 421 421 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Endosome; Glycoprotein; Membrane; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 448 AA 
Protein Sequence
MDVRRPIREA VNNRRKPKFL SVSFNQDDSC FSVALENGFR IFNTDPLTSK LSKTFKESAT 60
NQSRGTGIGY TRMLYRTNYI ALVGGGKRPR HALNKLIIWD DLLQKETITL KFMSSIKDVF 120
LSRIHIVVVL ENTIEIFQFQ TNPQRICPIL DIPPNGSVDY VVCSSKHLQS QASQSQSKIL 180
EIIAFPSNKC VGQIQVADLS QIKYNSQNPK ESALLPTSII KAHKNPIKLV RLNRQGTMVA 240
TCSVQGTLIR IFSTHNGTLI KEFRRGVDKA DIYEMSFSPN GSKLAVLSNK QTLHIFQIFE 300
TTNTETNTPD HSRANGSSHP LKNYIPKGLW RPKYLDSVWS ICNAHLKNPI FDAHRNDNSG 360
DVTHDNEFYK DRCRIGWCQD SNNREQDDSL VLVWQNSGIW EKFVILEKEQ QDSSKTHYSL 420
NESLRNEDTK SAGEPTRWEL VRESWREL 448 
Gene Ontology
 GO:0005768; C:endosome; IDA:SGD.
 GO:0019898; C:extrinsic to membrane; IDA:SGD.
 GO:0000324; C:fungal-type vacuole; IDA:SGD.
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0031090; C:organelle membrane; IBA:RefGenome.
 GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IBA:RefGenome.
 GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD.
 GO:0042594; P:response to starvation; IBA:RefGenome. 
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
  
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS