| Tag | Content |
|---|
| CPLM ID | CPLM-006206 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA-dihydrouridine synthase A |
Protein Synonyms/Alias | |
Gene Name | dusA |
Gene Synonyms/Alias | yjbN; b4049; JW5950 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 138 | VSIPVTVKTRIGIDD | acetylation | [1] | | 324 | NVLEHALKLVADKR* | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. |
Sequence Annotation | |
Keyword | Complete proteome; FAD; Flavoprotein; Oxidoreductase; Reference proteome; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 330 AA |
Protein Sequence | MPEKTDVHWS GRFSVAPMLD WTDRHCRYFL RLLSRNTLLY TEMVTTGAII HGKGDYLAYS 60
EEEHPVALQL GGSDPAALAQ CAKLAEARGY DEINLNVGCP SDRVQNGMFG ACLMGNAQLV 120
ADCVKAMRDV VSIPVTVKTR IGIDDQDSYE FLCDFINTVS GKGECEMFII HARKAWLSGL 180
SPKENREIPP LDYPRVYQLK RDFPHLTMSI NGGIKSLEEA KAHLQHMDGV MVGREAYQNP 240
GILAAVDREI FGSSDTDADP VAVVRAMYPY IERELSQGTY LGHITRHMLG LFQGIPGARQ 300
WRRYLSENAH KAGADINVLE HALKLVADKR 330 |
Gene Ontology | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. GO:0017150; F:tRNA dihydrouridine synthase activity; IMP:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |