| Tag | Content |
|---|
| CPLM ID | CPLM-024517 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 729 |
Protein Synonyms/Alias | |
Gene Name | ZNF729 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 374 | EIIHTGEKPYKCEEC | ubiquitination | [1] | | 402 | KVVHTGEKPYKCEEC | ubiquitination | [1] | | 420 | FSQFSTLKKHKIIHT | ubiquitination | [1] | | 421 | SQFSTLKKHKIIHTG | ubiquitination | [1] | | 601 | HTREKLYKCEECGKA | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 13 84 KRAB.
ZN_FING 180 202 C2H2-type 1.
ZN_FING 208 230 C2H2-type 2; degenerate.
ZN_FING 236 258 C2H2-type 3; degenerate.
ZN_FING 264 286 C2H2-type 4.
ZN_FING 292 314 C2H2-type 5.
ZN_FING 320 342 C2H2-type 6.
ZN_FING 348 370 C2H2-type 7; degenerate.
ZN_FING 376 398 C2H2-type 8.
ZN_FING 404 426 C2H2-type 9.
ZN_FING 432 454 C2H2-type 10.
ZN_FING 460 482 C2H2-type 11.
ZN_FING 488 510 C2H2-type 12.
ZN_FING 516 538 C2H2-type 13.
ZN_FING 544 566 C2H2-type 14.
ZN_FING 572 594 C2H2-type 15.
ZN_FING 600 622 C2H2-type 16.
ZN_FING 628 650 C2H2-type 17.
ZN_FING 656 678 C2H2-type 18.
ZN_FING 684 706 C2H2-type 19.
ZN_FING 712 734 C2H2-type 20.
ZN_FING 740 762 C2H2-type 21.
ZN_FING 768 790 C2H2-type 22.
ZN_FING 796 818 C2H2-type 23.
ZN_FING 824 846 C2H2-type 24.
ZN_FING 852 874 C2H2-type 25.
ZN_FING 880 902 C2H2-type 26.
ZN_FING 908 930 C2H2-type 27.
ZN_FING 936 958 C2H2-type 28.
ZN_FING 964 986 C2H2-type 29.
ZN_FING 992 1014 C2H2-type 30.
ZN_FING 1020 1042 C2H2-type 31.
ZN_FING 1048 1070 C2H2-type 32.
ZN_FING 1076 1098 C2H2-type 33.
ZN_FING 1104 1126 C2H2-type 34.
ZN_FING 1132 1154 C2H2-type 35; degenerate. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1173 AA |
Protein Sequence | MPGAPGSLEM GPLTFRDVTI EFSLEEWQCL DTVQQNLYRD VMLENYRNLV FLGMAVFKPD 60
LITCLKQGKE PWNMKRHEMV TKPPVMRSHF TQDLWPDQST KDSFQEVILR TYARCGHKNL 120
RLRKDCKSAN EGKMHKEGYN KLNQCRTATQ RKIFQCNKHM KVFHKYSNRN KVRHTKKKTF 180
KCIKCSKSFF MLSCLIRHKR IHIRQNIYKC EERGKAFKSF STLTKHKIIH TEDKPYKYKK 240
CGNAFKFSST FTKHKRIHTG ETPFRCEECG KAFNQSSNLT DHKRIHTGEK TYKCEECGKA 300
FKGSSNFNAH KVIHTAEKPY KCEDCGKTFN HFSALRKHKI IHTGKKPYKR EECGKAFSQS 360
STLRKHEIIH TGEKPYKCEE CGKAFKWSSK LTVHKVVHTG EKPYKCEECG KAFSQFSTLK 420
KHKIIHTGKK PYKCEECGKA FNSSSTLMKH KIIHTGEKPY KCEECGKAFR QSSHLTRHKA 480
IHTGEKPYKC EECGKAFNHF SDLRRHKIIH TGKKPYKCEE CGKAFSQSST LRNHQIIHTG 540
EKPYKCEECG KAFKWSSKLT VHKVIHTGEK PCKCEECGKA FKHFSALRKH KVIHTREKLY 600
KCEECGKAFN NSSILAKHKI IHTGKKPYKC EECGKAFRQS SHLTRHKAIH TGEKPYKCEE 660
CGKAFSHFSA LRRHKIIHTG KKPYKCEECG KAFSHFSALR RHKIIHTGEK PYKCEECGKA 720
FKWSSKLTVH KVIHTAEKPC KCEECGKSFK HFSALRKHKV IHTREKLYKC EECVKAFNSF 780
SALMKHKVIH TGEKPYKCEE CGKAFKWSSK LTVHKVIHTG EKPCKCEECG KAFKHFSALR 840
KHKIIHTGEK PYKCEECGKA FHQSSKLAKH KKIHTGEKPY KCEECGKAFN RLSHLTTHKI 900
IHTGKKPYKC EECGKAFNQS ANLTTHKRIH TGEKPYKCEE CGRAFSQSST LTAHKIIHAG 960
EKPYKCEECG KAFSQSSTLT THKIIHTGEK FYKCEECGKA FSQLSHLTTH KRIHSGEKPY 1020
KCEECGKAFK QSSTLTTHKR IHAGEKFYKC EVCSKAFSRF SHLTTHKRIH TGEKPYKCEE 1080
CGKAFNLSSQ LTTHKIIHTG EKPYKCEECG KAFNQSSTLS KHKVIHTGEK PYKYEECGKA 1140
FNQSSHLTTH KMIHTGEKPY KYKIIHTGEK PYK 1173 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |