CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035919
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glucosamine-6-phosphate isomerase 1 
Protein Synonyms/Alias
  
Gene Name
 GNPDA1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
67DLSFKYVKTFNMDEYubiquitination[1, 2, 3, 4]
126DAFEEKIKAAGGIELubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 138 AA 
Protein Sequence
MKLIILEHYS QASEWAAKYI RNRIIQFNPG PEKYFTLGLP TGSTPLGCYK KLIEYYKNGD 60
LSFKYVKTFN MDEYVGLPRD HPESYHSFMW NNFFKHIDIH PENTHILDGN AVDLQAECDA 120
FEEKIKAAGG IELFVGGI 138 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0004342; F:glucosamine-6-phosphate deaminase activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
 GO:0006044; P:N-acetylglucosamine metabolic process; IEA:InterPro. 
Interpro
 IPR006148; Glc/Gal-6P_isomerase.
 IPR004547; Glucosamine6P_isomerase. 
Pfam
 PF01182; Glucosamine_iso 
SMART
  
PROSITE
  
PRINTS