CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027755
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Some homology with holliday junction DNA helicase RUVB like 
Protein Synonyms/Alias
  
Gene Name
 CHTF18 
Gene Synonyms/Alias
 RUVBL 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
650LLSILNRKGPQEVGPubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Helicase; Hydrolase; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1184 AA 
Protein Sequence
MHVNASARRW GRGGAAALPG PAASPRRPAP RTGPVGRPTL APSPSRAHAH AKTNLLPGRA 60
VQAPDAVPGA GSSRAPARWR PRDPGSSAPD AWQRFRPAPL RAQPRPPPRP APGPPPPRKG 120
GCGGQWRAPQ DRTRGLRSRN SPRPPLAQPR LRHANQWRAP PGTPAADWRR PARSGRAVRD 180
GGGGAGGSER ELGLADGMED YEQELCGVED DFHNQFAAEL EVLAELEGAS TPSPSGVPLF 240
TAGRPPRTFE EALARGDAAS SPAPAASVGS SQGGARKRQV DADLQPAGSL PHAPRIKRPR 300
LQVVKRLNFR SEEMEEPPPP DSSPTDITPP PSPEDLAELW GHGVSEAAAD VGLTRASPAA 360
RNPVLRRPPI LEDYVHVTST EGVRAYLVLR ADPMAPGVQG SLLHVPWRGG GQLDLLGVSL 420
ASLKKQVDGE RRERLLQEAQ KLSDTLHRSG EEEAAQPLGA PEEEPTDGQD ASSHCLWVDE 480
FAPRHYTELL SDDFTNRCLL KWLKLWDLVV FGHERPSRKP RPSVEPARVS KEATAPGKWK 540
SHEQVLEEML EAGLDPSQRP KQKVALLCGP PGLGKTTLAH VIARHAGYSV VEMNASDDRS 600
PEVFRTRIEA ATQMESVLGA GGKPNCLVID EIDGAPVAAI NVLLSILNRK GPQEVGPQGP 660
AVPSGGGRRR RAEGGLLMRP IICICNDQFA PSLRQLKQQA FLLHFPPTLP SRLVQRLQEG 720
MRADPGVLAA LCEKTDNDIR ACINTLQFLY SRGQRELSVR DVQATRVGLK DQRRGLFSVW 780
QEVFQLPRAQ RSSQHVSVLT CHGTPGDAGL VVLQDMGDAG LGLWDVLLLA WTRRGTFPGR 840
FYRVLHAAAS AGEHEKVVQG LFDNFLRLRL RDSSLGAVCV ALDWLAFDDL LAGAAHHSQS 900
FQLLRYPPFL PVAFHVLFAS SHTPRITFPS SQQEAQNRMS QMRNLIQTLV SGIAPATRSR 960
ATPQALLLDA LCLLLDILAP KLRPVSTQLY STREKQQLAS LVGTMLAYSL TYRQERTPDG 1020
QYIYRLEPNV EELCRFPELP ARKPLTYQTK QLIAREIEVE KMRRAEASAR VENSPQVDGS 1080
PPGLEGLLGG IGEKGVHRPA PRNHEQRLEH IMRRAAREEQ PEKDFFGRVV VRSTAVPSAG 1140
DTAPEQDSVE RRMGTAVGRS EVWFRFNEGV SNAVRRSLYI RDLL 1184 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004386; F:helicase activity; IEA:UniProtKB-KW. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA 
SMART
 SM00382; AAA 
PROSITE
  
PRINTS