CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027028
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG8258 
Protein Synonyms/Alias
 LD24495p 
Gene Name
 CG8258, Dmel_CG8258 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
318MAVRLNSKFDLRRLSacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 546 AA 
Protein Sequence
MALSVPKAPG VSQMLKDGAR MYSGLEEAVF RNISACKEFA QTMRSAYGPN GMNKMIINHI 60
EKQFVTSDAG TIMRELDVEH PAAKLIVMAS QMQDAEVGDG TNFVVVLAGA LLESAEELLR 120
LGITTAEISD GYEKALEKAL EILPNLVSHK IEDYRNVEKV KEVLRTSIMS KQYGQEDFLN 180
DLVSKACVSI LPDEGTFNVD NIRICKILGS GLTKSEVVRG MVFKRFVEGD VTYAEKAKIV 240
IFSCPVDIIQ TETKGTVLIK SADELLSFSS GEESLLESQI KAIADAGVKV VVAGGKVGDM 300
ALHFLNKYGL MAVRLNSKFD LRRLSRSVNA TVLPRITTPS QEELGYCDKV CIEELGDTTI 360
VAFRNEGKDS RIATVVIRGA TDNFMDDIER ALDDAINNFK CLTRDGRYLP GAGATEIELA 420
TQLSAYADTL PGLDQYAVRK FANALEVFPK ALAENSGING TEIVNQLYLA HNNEAGKTIG 480
FDIEAEKAST IDTTKAKLFD LYQSKFWGLK YAVGAAATIL KVDQIIMAKR AGGPKVRQAA 540
GSDDES 546 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:EC.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0031122; P:cytoplasmic microtubule organization; IMP:FlyBase.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012721; Chap_CCT_theta.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00995; TCP1_3 
PRINTS
 PR00304; TCOMPLEXTCP1.