CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034349
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Gm2046 
Protein Synonyms/Alias
  
Gene Name
 Gm2046 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
104PDEARSLKAYGELPEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Initiation factor; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 144 AA 
Protein Sequence
MPKNKGKGGK NRRRGKNENE SEKRELVFKE YGQEYAQVTK MLGCGWLEAM CFDGVRRLCH 60
IRGKLRKKVW INTSDIILIG LRDYQDNRAD IILKYNPDEA RSLKAYGELP EHAKINEMDT 120
FGAGDDEEIV FDDIGEDDED IDDI 144 
Gene Ontology
 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. 
Interpro
 IPR012340; NA-bd_OB-fold.
 IPR006196; RNA-binding_domain_S1_IF1.
 IPR001253; TIF_eIF-1A.
 IPR018104; TIF_eIF-1A_CS. 
Pfam
 PF01176; eIF-1a 
SMART
 SM00652; eIF1a 
PROSITE
 PS01262; IF1A
 PS50832; S1_IF1_TYPE 
PRINTS