| Tag | Content |
|---|
| CPLM ID | CPLM-002357 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA polymerase III subunit tau |
Protein Synonyms/Alias | DNA polymerase III subunit gamma |
Gene Name | dnaX |
Gene Synonyms/Alias | dnaZ; dnaZX; b0470; JW0459 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 100 | IDAASRTKVEDTRDL | acetylation | [1] | | 161 | LATTDPQKLPVTILS | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. |
Sequence Annotation | NP_BIND 45 52 ATP (Potential). |
Keyword | 3D-structure; ATP-binding; Complete proteome; Direct protein sequencing; DNA replication; DNA-directed DNA polymerase; Nucleotide-binding; Nucleotidyltransferase; Reference proteome; Ribosomal frameshifting; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 643 AA |
Protein Sequence | MSYQVLARKW RPQTFADVVG QEHVLTALAN GLSLGRIHHA YLFSGTRGVG KTSIARLLAK 60
GLNCETGITA TPCGVCDNCR EIEQGRFVDL IEIDAASRTK VEDTRDLLDN VQYAPARGRF 120
KVYLIDEVHM LSRHSFNALL KTLEEPPEHV KFLLATTDPQ KLPVTILSRC LQFHLKALDV 180
EQIRHQLEHI LNEEHIAHEP RALQLLARAA EGSLRDALSL TDQAIASGDG QVSTQAVSAM 240
LGTLDDDQAL SLVEAMVEAN GERVMALINE AAARGIEWEA LLVEMLGLLH RIAMVQLSPA 300
ALGNDMAAIE LRMRELARTI PPTDIQLYYQ TLLIGRKELP YAPDRRMGVE MTLLRALAFH 360
PRMPLPEPEV PRQSFAPVAP TAVMTPTQVP PQPQSAPQQA PTVPLPETTS QVLAARQQLQ 420
RVQGATKAKK SEPAAATRAR PVNNAALERL ASVTDRVQAR PVPSALEKAP AKKEAYRWKA 480
TTPVMQQKEV VATPKALKKA LEHEKTPELA AKLAAEAIER DPWAAQVSQL SLPKLVEQVA 540
LNAWKEESDN AVCLHLRSSQ RHLNNRGAQQ KLAEALSMLK GSTVELTIVE DDNPAVRTPL 600
EWRQAIYEEK LAQARESIIA DNNIQTLRRF FDAELDEESI RPI 643 |
Gene Ontology | GO:0043846; C:DNA polymerase III, clamp loader complex; IDA:EcoliWiki. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0016887; F:ATPase activity; IDA:EcoliWiki. GO:0003677; F:DNA binding; IEA:InterPro. GO:0030337; F:DNA polymerase processivity factor activity; IDA:EcoliWiki. GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW. GO:0006260; P:DNA replication; IMP:EcoliWiki. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |