UniProt Accession

 Q6FGM0_HUMAN; Q6FGM0 

Genbank Protein ID

 BC098565; AY364240; AK315450; CR542087; CH471139; CH471139 

Genbank Nucleotide ID

 AAH98565.1; AAQ76799.1; BAG37838.1; CAG46884.1; EAW69228.1; EAW69229.1 

Protein Name

 SH3 domain GRB2-like 1 

Protein Synonyms/Alias

 SH3-domain GRB2-like 1; SH3-domain GRB2-like 1, isoform CRA_b; SH3GL1 protein; cDNA, FLJ96508, Homo sapiens SH3-domain GRB2-like 1 (SH3GL1), mRNA 

Gene Name

 SH3GL1 

Gene Synonyms/Alias

 hCG_21932 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
76	TMLNTVSKIRGQVKN	ubiquitination	[1]
239	ILDELAEKLKRRMRE	ubiquitination	[2]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 SH3 domain. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 368 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA. 

Interpro

 IPR027267; AH/BAR-dom.
 IPR004148; BAR_dom.
 IPR000108; p67phox.
 IPR001452; SH3_domain. 

Pfam

 PF03114; BAR
 PF00018; SH3_1 

SMART

 SM00721; BAR
 SM00326; SH3 

PROSITE

 PS51021; BAR
 PS50002; SH3 

PRINTS

 PR00499; P67PHOX.
 PR00452; SH3DOMAIN.