CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035802
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Zfyve16 
Protein Synonyms/Alias
  
Gene Name
 Zfyve16 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1402DSEERKNKGVISSVDubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1547 AA 
Protein Sequence
MDSYFKAAVS DLDKLLDDFE QNPEKQDYFQ DVQDVYAFNQ CSVSSELASP QLALLSKDQR 60
CISSHASSET CCEANETFLQ GKIPEGLTSK QNEKNVAGLD LLSSVDASTS DEIQPSCMRR 120
CSKPVCDLIS DMGNLVHATS SEEDIKQLLP DDSKSPADTL ITLDSSSVSE VLIGLDLSSV 180
SDTLAVSSVD GGSQAVRKEQ DTNAGVQSRD NSRIQESGAE VDMALSDSCK YSRTENLKDK 240
MISNELETVD FGMPSVLTEQ SSEMSNTKDS PQYQRLPCEL LKDDGDLAEE KVGMAGNSTK 300
CLEEGGNIIA MPCKLPKNEE ISPNDPTSKD ENFKLPDFSV QESRTAVFIK QTVAEDSVKS 360
DLKDNNDVVQ VSSSSLHVSS DGVSPSLSCL SLSGSLCGSL VDCNAHGDFL PSDESKGQNN 420
DAVTAHEEIQ KSAALDGETD LLKKEKQESM FLQPVNDKEG DGEVELEEMV ISGEPLEYPE 480
GTNPAAAGSQ MAPPTVSASE APGQCEALTF SSGDMDGQEL DYFNIDESMR SGILVSDAEL 540
DAFLKEQSLQ NSNTMSFGEN ASDSQLQMNQ IDMKGLCDEN AGDRYFNAEA GAAGESGGVV 600
ICETTDKENT VQNGGLSVGE KSAIPTERGL SASQPDIRSE VPVPSINTQA VGGARPKQLP 660
SRPPGTSSSQ GPSKPHVVGV PAGEPSTANA AAAPTRPADH TPDSQVSFNS NYIDIESNFE 720
GGSSFVTANK DSLPENIRKE GLVLGQKQPT WVPDSEAPNC MNCKVKFTFT KRRHHCRACG 780
KVFCGVCCNR KCKLQYLEKE ARVCVICYET INKAQAFERM MSPGGACLKS NHSNECVTAQ 840
PLQETQTSSI PSPTALPISA LKQPNVEGPC SREQKRVWFA DGILPNGEVA DTTKLSSGSK 900
RCSDDFSPVL PDAPTVINKV DHTPSPMVEK ANNSVGDVLR SEITQSPICR AAPLEILPGS 960
TGAEGLPTAG PFTLEDDVFV DSEEPSTPTV VPANTGLPVA SVSDYRLLCG VAKCVCNNIS 1020
LLPDDDVGLP PLLATSGEDG SVPVVQEHPS HEQIILLLES EGFPPATFVL NANLLVNVKL 1080
VFYSSDKYWY FSTNGLHGLG QAEIIILLLC LPNEDTVPKD IFRLFITIYK DASKGKYVEN 1140
LDNLTFTESF LSSKDHGGFL FITPTFQKLD DLPVPRSPFL CGILIHKLEI PWAKAFPMRL 1200
MLRLGAEYKA YPAPLTSVRG RRPLFGEIGH TIMNLLVDLR NYQYTLHNID QLLIHMEMGK 1260
SCIKIPRKKY SDVLKVINSS NEHVISIGAS FSTEADSHLV CVQSDGVYQT QANSATGQPR 1320
KVTGASFVVF NGALKTSSGF LAKSSIVEDG LMVQITPETM DGLRLALREQ KDFKIQCGKV 1380
DAVDLREYVD ICWVDSEERK NKGVISSVDG MSLEGFPSEK IKLETDFETE EKTVKCTEVF 1440
CFLKDQDISL SSSSYQFAKE IATACSAALC PHLRTLKSNR MNRIGLRVSV DTDMVEFQAG 1500
CEGQLLPQHY LNDLDSALIP VIHGGTSNST VPLEIELAFF ILENLLE 1547 
Gene Ontology
 GO:0005769; C:early endosome; IEA:Compara.
 GO:0005545; F:1-phosphatidylinositol binding; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Compara.
 GO:0008565; F:protein transporter activity; IEA:Compara.
 GO:0016197; P:endosomal transport; IEA:Compara.
 GO:0006622; P:protein targeting to lysosome; IEA:Compara. 
Interpro
 IPR022557; DUF3480.
 IPR000306; Znf_FYVE.
 IPR017455; Znf_FYVE-rel.
 IPR011011; Znf_FYVE_PHD.
 IPR017165; Znf_FYVE_SARA/endofin.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF11979; DUF3480
 PF01363; FYVE 
SMART
 SM00064; FYVE 
PROSITE
 PS50178; ZF_FYVE 
PRINTS