| Tag | Content |
|---|
| CPLM ID | CPLM-019137 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Reticulocalbin-3 |
Protein Synonyms/Alias | EF-hand calcium-binding protein RLP49 |
Gene Name | RCN3 |
Gene Synonyms/Alias | UNQ239/PRO272 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 66 | FLGREVAKEFDQLTP | ubiquitination | [1] |
|
Reference | [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C. Nat Cell Biol. 2012 Oct;14(10):1089-98. [ PMID: 23000965] |
Functional Description | |
Sequence Annotation | DOMAIN 75 112 EF-hand 1.
DOMAIN 113 148 EF-hand 2.
DOMAIN 163 198 EF-hand 3.
DOMAIN 200 235 EF-hand 4.
DOMAIN 241 276 EF-hand 5.
DOMAIN 277 312 EF-hand 6.
MOTIF 325 328 Prevents secretion from ER (Potential).
CARBOHYD 140 140 N-linked (GlcNAc...). |
Keyword | Calcium; Complete proteome; Endoplasmic reticulum; Glycoprotein; Metal-binding; Polymorphism; Reference proteome; Repeat; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 328 AA |
Protein Sequence | MMWRPSVLLL LLLLRHGAQG KPSPDAGPHG QGRVHQAAPL SDAPHDDAHG NFQYDHEAFL 60
GREVAKEFDQ LTPEESQARL GRIVDRMDRA GDGDGWVSLA ELRAWIAHTQ QRHIRDSVSA 120
AWDTYDTDRD GRVGWEELRN ATYGHYAPGE EFHDVEDAET YKKMLARDER RFRVADQDGD 180
SMATREELTA FLHPEEFPHM RDIVIAETLE DLDRNKDGYV QVEEYIADLY SAEPGEEEPA 240
WVQTERQQFR DFRDLNKDGH LDGSEVGHWV LPPAQDQPLV EANHLLHESD TDKDGRLSKA 300
EILGNWNMFV GSQATNYGED LTRHHDEL 328 |
Gene Ontology | GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell. GO:0005509; F:calcium ion binding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |