CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004011
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serum amyloid P-component 
Protein Synonyms/Alias
 SAP 
Gene Name
 Apcs 
Gene Synonyms/Alias
 Ptx2; Sap 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
75SLFSYSVKGRDNELLubiquitination[1]
146LQREYTVKAPPSIVLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 21 224 Pentaxin.
 METAL 78 78 Calcium 1 (By similarity).
 METAL 79 79 Calcium 1 (By similarity).
 METAL 156 156 Calcium 1 (By similarity).
 METAL 156 156 Calcium 2 (By similarity).
 METAL 157 157 Calcium 1; via carbonyl oxygen (By
 METAL 158 158 Calcium 1 (By similarity).
 METAL 158 158 Calcium 2 (By similarity).
 METAL 168 168 Calcium 2 (By similarity).
 CARBOHYD 52 52 N-linked (GlcNAc...).
 DISULFID 56 115 By similarity.  
Keyword
 Amyloid; Calcium; Complete proteome; Disulfide bond; Glycoprotein; Lectin; Metal-binding; Reference proteome; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 224 AA 
Protein Sequence
MDKLLLWMFV FTSLLSEAFC QTDLKRKVFV FPRESETDHV KLIPHLEKPL QNFTLCFRTY 60
SDLSRSQSLF SYSVKGRDNE LLIYKEKVGE YSLYIGQSKV TVRGMEEYLS PVHLCTTWES 120
SSGIVEFWVN GKPWVKKSLQ REYTVKAPPS IVLGQEQDNY GGGFQRSQSF VGEFSDLYMW 180
DYVLTPQDIL FVYRDSPVNP NILNWQALNY EINGYVVIRP RVWD 224 
Gene Ontology
 GO:0031012; C:extracellular matrix; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006461; P:protein complex assembly; IEA:Compara. 
Interpro
 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR001759; Pentaxin. 
Pfam
 PF00354; Pentaxin 
SMART
 SM00159; PTX 
PROSITE
 PS00289; PENTAXIN 
PRINTS
 PR00895; PENTAXIN.