| Tag | Content |
|---|
| CPLM ID | CPLM-023739 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Thioredoxin-related transmembrane protein 2 |
Protein Synonyms/Alias | Cell proliferation-inducing gene 26 protein; Thioredoxin domain-containing protein 14 |
Gene Name | TMX2 |
Gene Synonyms/Alias | TXNDC14; CGI-31; My009; PIG26; PSEC0045; UNQ237/PRO270 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 106 | YIKYFNDKTIDEELE | ubiquitination | [1] | | 177 | VSTSPLTKQLPTLIL | ubiquitination | [1] | | 189 | LILFQGGKEAMRRPQ | ubiquitination | [1] | | 231 | QRAKKLSKAGDNIPE | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | |
Sequence Annotation | DOMAIN 114 269 Thioredoxin.
MOTIF 293 296 Di-lysine motif.
MOD_RES 243 243 Phosphoserine.
MOD_RES 288 288 Phosphoserine. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 296 AA |
Protein Sequence | MAVLAPLIAL VYSVPRLSRW LAQPYYLLSA LLSAAFLLVR KLPPLCHGLP TQREDGNPCD 60
FDWREVEILM FLSAIVMMKN RRSMFLMTCK PPLYMGPEYI KYFNDKTIDE ELERDKRVTW 120
IVEFFANWSN DCQSFAPIYA DLSLKYNCTG LNFGKVDVGR YTDVSTRYKV STSPLTKQLP 180
TLILFQGGKE AMRRPQIDKK GRAVSWTFSE ENVIREFNLN ELYQRAKKLS KAGDNIPEEQ 240
PVASTPTTVS DGENKKDK 258 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0045454; P:cell redox homeostasis; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |