| Tag | Content |
|---|
| CPLM ID | CPLM-008293 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein mlc |
Protein Synonyms/Alias | Making large colonies protein |
Gene Name | mlc |
Gene Synonyms/Alias | b1594; JW1586 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 312 | LRGDLLAKDIITGVG | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Transcriptional repressor that regulates the expression of proteins that are part of the phosphotransferase system for sugar uptake. Regulates the expression of malT. |
Sequence Annotation | DNA_BIND 33 42 H-T-H motif (By similarity).
METAL 247 247 Zinc.
METAL 257 257 Zinc.
METAL 259 259 Zinc.
METAL 264 264 Zinc. |
Keyword | 3D-structure; Carbohydrate metabolism; Complete proteome; DNA-binding; Metal-binding; Reference proteome; Transcription; Transcription regulation; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 406 AA |
Protein Sequence | MVAENQPGHI DQIKQTNAGA VYRLIDQLGP VSRIDLSRLA QLAPASITKI VREMLEAHLV 60
QELEIKEAGN RGRPAVGLVV ETEAWHYLSL RISRGEIFLA LRDLSSKLVV EESQELALKD 120
DLPLLDRIIS HIDQFFIRHQ KKLERLTSIA ITLPGIIDTE NGIVHRMPFY EDVKEMPLGE 180
ALEQHTGVPV YIQHDISAWT MAEALFGASR GARDVIQVVI DHNVGAGVIT DGHLLHAGSS 240
SLVEIGHTQV DPYGKRCYCG NHGCLETIAS VDSILELAQL RLNQSMSSML HGQPLTVDSL 300
CQAALRGDLL AKDIITGVGA HVGRILAIMV NLFNPQKILI GSPLSKAADI LFPVISDSIR 360
QQALPAYSQH ISVESTQFSN QGTMAGAALV KDAMYNGSLL IRLLQG 406 |
Gene Ontology | GO:0005737; C:cytoplasm; TAS:EcoCyc. GO:0003677; F:DNA binding; IDA:EcoCyc. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0016052; P:carbohydrate catabolic process; IMP:EcoCyc. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IDA:EcoCyc. |
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