CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031046
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ55992, highly similar to GTPase, IMAP family member 5 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
44MGGFQRGKYGTMAEGubiquitination[1]
76VGKTGCGKSATGNSIubiquitination[1]
92GQPVFESKLRAQSVTubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 343 AA 
Protein Sequence
MELSAPAHGS SLTASAQPPS VTATLEDRAQ QPFLERMGGF QRGKYGTMAE GRSEDNLSAT 60
PPALRIILVG KTGCGKSATG NSILGQPVFE SKLRAQSVTR TCQVKTGTWN GRKVLVVDTP 120
SIFESQADTQ ELYKNIGDCY LLSAPGPHVL LLVIQLGRFT AQDTVAIRKV KEVFGTGAMR 180
HVVILFTHKE DLGGQALDDY VANTDNCSLK DLVRECERRY CAFNNWGSVE EQRQQQAELL 240
AVIERLGRER EGSFHSNDLF LDAQLLQRTG AGACQEDYRQ YQAKVEWQVE KHKQELRENE 300
SNWAYKALLR VKHLMLLHYE IFVFLLLCSI LFFIIFLFIF HYI 343 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0043011; P:myeloid dendritic cell differentiation; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0032689; P:negative regulation of interferon-gamma production; IEA:Compara.
 GO:0050995; P:negative regulation of lipid catabolic process; IEA:Compara.
 GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IEA:Compara.
 GO:0050868; P:negative regulation of T cell activation; IEA:Compara.
 GO:0010524; P:positive regulation of calcium ion transport into cytosol; IEA:Compara.
 GO:0032831; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IEA:Compara.
 GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Compara.
 GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Compara.
 GO:0045838; P:positive regulation of membrane potential; IEA:Compara.
 GO:0002729; P:positive regulation of natural killer cell cytokine production; IEA:Compara.
 GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Compara.
 GO:0046902; P:regulation of mitochondrial membrane permeability; IEA:Compara.
 GO:0030217; P:T cell differentiation; IEA:Compara.
 GO:0043029; P:T cell homeostasis; IEA:Compara.
 GO:0001659; P:temperature homeostasis; IEA:Compara. 
Interpro
 IPR006703; AIG1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF04548; AIG1 
SMART
  
PROSITE
  
PRINTS