CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016021
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar protein sorting-associated protein 13B 
Protein Synonyms/Alias
 Cohen syndrome protein 1 homolog 
Gene Name
 Vps13b 
Gene Synonyms/Alias
 Coh1; Kiaa0532 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
571DLGIVQEKSTKSLVIubiquitination[1]
842PMTGVKSKNPLPTLEubiquitination[1]
1602LRKDIYQKALNLGILubiquitination[1]
1767ISKQEQKKVDTFDGGubiquitination[1]
2053KANLSFTKLDQINHFubiquitination[1]
2282QMPSPVEKTQAFKTEubiquitination[1]
2287VEKTQAFKTEQSSDDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May be involved in protein sorting in post Golgi membrane traffic (By similarity). 
Sequence Annotation
 MOD_RES 998 998 Phosphoserine.
 MOD_RES 1001 1001 Phosphoserine.  
Keyword
 Complete proteome; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 4013 AA 
Protein Sequence
MLESYVTPIL MSYVNRYIKN LKPSDLQLSL WGGDVVLSKL ELKLDVLEQE LKLPFTFLSG 60
HIHELRIHVP WTKLGSEPVV ITINTMECIL KLKDGIQDDH ESCGSNSTNR STAENTKSSI 120
KPRRIQQAAP ADPDLPPGYV QSLIRRVVNN VNIVINNLIL KYVEDDIVLS VNITSAECYT 180
VGELWDRAFM DISATDLVLR KAINFSDCTV CLDKRNASGK IEFYQDPLLY KCSFRTRLHF 240
TYDNLNSKMP SVIKIHTLVE SLKLSITDQQ LPMFIRIMQL GIALYYGEIG NFKDGETEDP 300
PCLSKDTLAN LTGTEEESRI DMQYPAPYKG QELYSQDYEE PQGWVSWAWS FVPAIVSYDD 360
GEEDDLGTDP ASIMHQQKAQ TLKDPIVSVG FYCTKATVTF KLTEMQAENS YYSPQKVKSK 420
EVLCWEQEGT TIEALMMGEP FFDCQIGFVG CRAMCLKGIL GVKDFEEHMN RSETEACFFI 480
CGENLSTKGL TYLTNSLFDY RSPENNGTRA EFILDAAHHK ETHTDIAGIQ RFGAFYMDYL 540
YTVEHSSGKG PTSQQDFPSG KNEDLGIVQE KSTKSLVIGP LDCRLDSSAV HRVLKMIVCA 600
LEHEYEPYSR LKPESKDEKE TVLDPEEVSS LEEYIPTRHT SVTLLKCTCT VFMAEFNLLD 660
CLLPVIMGGK NSSNVTNATN FQSLRPLPSI QILVDKINLE HSVPMYAEQL VHVVSSLNQP 720
SDNLLHYCYV HCYLKVFGFQ AGLTCLDHSG SYCLPAPIIP SFSTALYGKL LKLPALWTKR 780
SQTVVTEGIF ELPNLTIQAT RAQTLLLQAI YQSWSHIGNV SSSTVNEALM NEVFPMTGVK 840
SKNPLPTLEG SIQNVELKYC STSLVKCASG TLGSIKICAK APGDSGKEKL IPLLQGPSDT 900
RDLHSSKWLN ESRKPESLLA PDLIAFTIQV PQYMDYCHHS GAVFLCSVQG LAVNIDPILY 960
TWVIYQPQKR ANRHAQQQPV VAVPLVTSVN RRKEDELSIG SAPLGKQQSY QASEYASSPI 1020
KTKTVTESRP VSVPVKAVLR VHEECRSPED KMKEFIAILW NAVKSLTLQL DVQSCCVFIP 1080
NDNLPSPSTI VSGDIPGTVR SWYHGQTSIP GTLVLCLPQI KIISAGHKYM EPLQEIPFVI 1140
PRPILEEGDA FPWTISLHHF SIYTLLGKQV TLSLVEPMGC TSTLAVTSQK LLPVGPDGRH 1200
SFVVCLHVDL ESLEIKCSNP QVQLIYELAD TMSKVWSKIQ KRGNLSPSSV YPETVAGPIP 1260
GSPVWSSVGT APPDTSTCSP SADIGTTTEG DSVQAGDDSP FSDSVTLEQT TSNIGGSSGR 1320
VSLWMQWVLP KATVKLFAPD LEKKGTEVCM VSELEDLSAS IDVQDVYTKV KCKVESFSID 1380
HYQSSLGEEC WGTGGAFLSC TELDTCTLLV RPLSKQDSSN CPAFLSSTTT KLLDGAHQQH 1440
GFLSLTYTKA VTKNVRHKLT SRNERRSFYK LSEGLMDGSP HFLHEILLSA QAFDIVVCFP 1500
LLNAIASVFH TKLPKTQREK RKSSGQPMRT HTLTSRNLPL IYINTSVIRI FVPQTEETQS 1560
TVAVNQAAKE DTMVLKVGSI AMAPQADNPL GRSVLRKDIY QKALNLGILR DPGSEIEDRQ 1620
YQIDLQSINI GTAQWDQLKP EKGSGSGGVP TESERNSQNP ALEWNMASSI QRHQERRAIL 1680
TPILTDFSVR ITGAPAIIFT KIISQENLHM EEILVCGHSL EVNITTNLDF FLSVAQVQLL 1740
HQLIVANMTG LEPSTKATEI SKQEQKKVDT FDGGTAETSS RYSGAQDSGI GSDSVKIRIV 1800
QIEQYSGASQ HRIARPSHQS SIVKNLNFIP FDIFITASRI SLMTYSSVAL PKFKLPEQKE 1860
DGKTGRTFLN LAEVDSDVAK PNQACVSMVT AEDPLSSSTS FSSGKKVRVL SLESLHASTR 1920
SSARQALGVT VVRQPGRRGT GDLELDLFLH LIVSQPSLLL SCHHRKQRVE VSIFDAMLKG 1980
VPSDYTCTDP GKTLPEASDY NIVWLQTVPG ETDSKSGIPP SLVTLHIKDF LNGPADIYLD 2040
VSKPLKANLS FTKLDQINHF LKKIKKAHSS AHSKETSTPS DSILNMDEPP VPKCYRGKLS 2100
KTKVHCDEAQ KTSFQENIWR AISCFQKVSV HTTQIVVSME TVPHPHKPCV LASLSNLNGS 2160
LTVKAAQKVP GASLGSSFLL SIHDVLLKTS LKERSRILIG PFSATVNLEA KWCKHSGNPG 2220
PQQSIPKISM DLRGGLLQVF WGQEHLNCLA LLHELFNGYL QEGKSEMPVP ESAPQMPSPV 2280
EKTQAFKTEQ SSDDLRTGIF QYVQDAESLK LPGVYEVLFY NETEESPGMM LWRYPEPRVL 2340
TLVRITPVPF NTTEDPDIST ADLGDVLQVP CGLEYWDELQ KVFVAFQEFS LSESKVCELQ 2400
LPDINLVHDQ KKLVSSDLWR IVLNNNQNTT DDQSSASESG SQSTCEPLVT PTALAACTRV 2460
DSCFTPWFVP SLCMSFQFAH LEFRLCHHLD QLGTASPQYL QPFISDKNVP SELEYMIISF 2520
REPNLHLRQW NSGPVCQEIK FSSQMDCKLL ECRNVTMQTV VKPFGICGQM ALSSDGVQKL 2580
LDSTVIVDSV LVNFGQHVVH SLNTAIQAWQ QNKCPEVEEL VFSHFVICND TQETLRFGQV 2640
DTDENILLAS LHSHQYSWRS HKSPQLLHIC IEGWGNWRWS EPFTVDHAGT FIRTIQYKGR 2700
TASLIIKVRA LSGVQKQIII CGRQIICSYL SQSIELKVVQ HYIGQDGQAV VREHFDCLTA 2760
KQKLPSYILE NNELTELCVK AKGDEDWSRD VCLEPKASEY STVIQVPTSN SSIIYVWCTV 2820
LTLEPNSQVQ QRMIVFSPLF IMRSHLPDPI IIHLEKRSLG LSETQIIPGR GQENPLQNVE 2880
PDLVHHLTFQ AREEYDPSDC AVPISTALIK QIATKIQPGG TVNEMLDEFY GPEKSQEPTW 2940
PYSNKDSDRN EQLSQWDSPM RVKLSIWKPY VRTLLIELLP WALLINQSKW DLWLFEGEKI 3000
VLQVPAGKII IPPNFQEAFQ IGIYWENTNT VHKTLAIKLV HNLTSPKWKD GGNGEVVTLD 3060
EEAFVDAEIR LGAFPGHQKL CQFCISSMVQ HGIQVIQIED KTTVINNTPY QIVYKPHLAI 3120
SNSYSGKEHC HVPDSATFSI CPGGEHPAVR SSSLPCWDVT PAVGSSELDT ATLQKQILLG 3180
FSPVPGADSA QCWSLPAIIG GEFPRQSVAV PFGTGRENGF CTRAIALTYQ EHLGVTYITL 3240
SEDPSPRVVF HNRCPVPMLM KENIRDIPKF DVYCKKIPPE SSVHHELYHQ IISYPDCKTK 3300
DLLPSLFLRI DSMEEMTAEW SDPVDINSQG TQVVFLTGFG YVYVDIAQQC GTVFIILAPE 3360
GKAGPIFTST SRALERMVTF RMFITQLSLA VSDDLTHQAP SELLRLTLDN VFLHVSPVPA 3420
LLPGEEPPSS FFQLYGVEVY CGDLQLDNQL YNKSNFHFAV LVCQGERTDP AQYSRVQSLL 3480
VSSKALEEYK ENCFIKLCLT VSEGKDILLD VSEFTFELKP ARLYVEDTFV YYIKTLFDTY 3540
LPPSRMSGHH AQLFTGQQVL PVQVTQHAKA LVNAVKLRKL LIQPVNLLIS IHASLKLYIA 3600
SDHTPLSFSV FERGPVFTTA RQLVHALAMH YAAGALFRAG WVVGSLEILG SPASLVRSIG 3660
NGISDFFRLP YEGLTRGPGA FVSGVSRGTT SFVKHISKGA LTSITNLATS LARNMGRLSL 3720
DEEHYNRQEE WRRQLPESLG EGLRQGLSRL GISLLGAIAG IVDQPMQNFQ KTSETQASAG 3780
HKAKGVISGV GKGIMGVFTK PIGGAAELVS QTGYGILHGA GLSQLPKQRC QPTHLYADQA 3840
PNSHVKYVWK MLQSLGRPEV HMALDVVLVR GSGQEHEGCL LLTSEVLFVV SISEDTQQQA 3900
FPITEISCAQ DTKQNNLLTV QLKQPRVASD VEIDGARERL SEQQFKRLVD YIAKTSCHLA 3960
PSCSSMQTCS VVAVEPPPAT VKTYHYLVDP HFAQVFISKF TMVKNKALRK GFS 4013 
Gene Ontology
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR015412; Autophagy-rel_C.
 IPR026847; VPS13.
 IPR026854; VPS13A_N.
 IPR009543; VPSAP_dom. 
Pfam
 PF09333; ATG_C
 PF12624; Chorein_N
 PF06650; DUF1162 
SMART
  
PROSITE
  
PRINTS