GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005730; C:nucleolus; IDA:HPA.
GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0043234; C:protein complex; IEA:Compara.
GO:0032184; F:SUMO polymer binding; IDA:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007389; P:pattern specification process; IEA:Compara.
GO:0031398; P:positive regulation of protein ubiquitination; IEA:Compara.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IEA:Compara.
GO:0000209; P:protein polyubiquitination; IEA:Compara.
GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IEA:Compara.