CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018933
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome c oxidase subunit 5A, mitochondrial 
Protein Synonyms/Alias
 Cytochrome c oxidase polypeptide Va 
Gene Name
 CoVa 
Gene Synonyms/Alias
 CG14724 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
46EFDKRYEKYFSREGIacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. 
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 149 AA 
Protein Sequence
MLSITARNLA SALRSSLVGT SSRVAAVRCL HGTEESAEEF DKRYEKYFSR EGIDGWEIRK 60
GMNDLLGMDL VPSPKIIEAG LRASRRVNDI ALAIRWLEGC KDKCGDQKAT LYPYLLEKIT 120
PTLQELGIPT IEELGYDKPE LALKSVYDA 149 
Gene Ontology
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:FlyBase.
 GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0045787; P:positive regulation of cell cycle; IMP:FlyBase. 
Interpro
 IPR003204; Cyt_c_oxidase_su5A/6. 
Pfam
 PF02284; COX5A 
SMART
  
PROSITE
  
PRINTS