CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036601
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone deacetylase 2 
Protein Synonyms/Alias
  
Gene Name
 HDAC2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
9AYSQGGGKKKVCYYYubiquitination[1, 2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 109 AA 
Protein Sequence
MAYSQGGGKK KVCYYYDVCV FSILGDIGNY YYGQGHPMKP HRIRMTHNLL LNYGLYRKME 60
IYRPHKATAE EMTKYHSDEY IKFLRSIRPD NMSEYSKQMQ RFNVGEDCP 109 
Gene Ontology
 GO:0004407; F:histone deacetylase activity; IEA:InterPro. 
Interpro
 IPR000286; His_deacetylse.
 IPR003084; His_deacetylse_1.
 IPR023801; His_deacetylse_dom. 
Pfam
 PF00850; Hist_deacetyl 
SMART
  
PROSITE
  
PRINTS
 PR01271; HISDACETLASE.