UniProt Accession

 SFT2C_HUMAN; Q587I9; Q8N2P9 

Genbank Protein ID

 AK074549; AC006011 

Genbank Nucleotide ID

 BAC11053.1; AAX82032.1 

Protein Name

 Vesicle transport protein SFT2C 

Protein Synonyms/Alias

 SFT2 domain-containing protein 3 

Gene Name

 SFT2D3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
16	QEYLAQGKAGGPAAA	ubiquitination	[1, 2]
31	EPLLAAEKAEEPGDR	ubiquitination	[1]
211	GRGAGLAKVLPV***	ubiquitination	[2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Polymorphism; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 215 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 

Interpro

 IPR007305; Vesicle_transpt_Got1/SFT2.
 IPR011691; Vesicle_transpt_SFT2. 

Pfam

 PF04178; Got1 

SMART

  

PROSITE

  

PRINTS