CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001934
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hemoglobin subunit beta 
Protein Synonyms/Alias
 Beta-globin; Hemoglobin beta chain 
Gene Name
 HBB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Bos taurus (Bovine) 
NCBI Taxa ID
 9913 
Lysine Modification
Position
Peptide
Type
References
81MKHLDDLKGTFAALSacetylation[1]
103HVDPENFKLLGNVLVacetylation[1]
Reference
 [1] The functional, oxygen-linked chloride binding sites of hemoglobin are contiguous within a channel in the central cavity.
 Ueno H, Manning JM.
 J Protein Chem. 1992 Apr;11(2):177-85. [PMID: 1326985
Functional Description
 Involved in oxygen transport from the lung to the various peripheral tissues. 
Sequence Annotation
 METAL 62 62 Iron (heme distal ligand).
 METAL 91 91 Iron (heme proximal ligand).  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport; Polymorphism; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 145 AA 
Protein Sequence
MLTAEEKAAV TAFWGKVKVD EVGGEALGRL LVVYPWTQRF FESFGDLSTA DAVMNNPKVK 60
AHGKKVLDSF SNGMKHLDDL KGTFAALSEL HCDKLHVDPE NFKLLGNVLV VVLARNFGKE 120
FTPVLQADFQ KVVAGVANAL AHRYH 145 
Gene Ontology
 GO:0005833; C:hemoglobin complex; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0019825; F:oxygen binding; IEA:InterPro.
 GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. 
Interpro
 IPR000971; Globin.
 IPR009050; Globin-like.
 IPR012292; Globin_dom.
 IPR002337; Haemoglobin_b. 
Pfam
 PF00042; Globin 
SMART
  
PROSITE
 PS01033; GLOBIN 
PRINTS
 PR00814; BETAHAEM.