CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026303
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transmembrane 9 superfamily member 3 
Protein Synonyms/Alias
  
Gene Name
 TM9SF3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
15HNRQETYKYFSLPFCubiquitination[1, 2]
27PFCVGSKKSISHYHEubiquitination[2]
116YYLWTYKKLEIGFNGubiquitination[2]
166KFEDRFDKYLDPSFFubiquitination[1]
213KDYARYSKEEEMDDMubiquitination[3, 4, 5]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [5] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 254 AA 
Protein Sequence
MNTVGPYHNR QETYKYFSLP FCVGSKKSIS HYHETLGEAL QGVELEFSGL DIKFKDDVMP 60
ATYCEIDLDK EKRDAFVYAI KNHYWYQMYI DDLPIWGIVG EADENGEDYY LWTYKKLEIG 120
FNGNRIVDVN LTSEGKVKLV PNTKIQMSYS VKWKKSDVKF EDRFDKYLDP SFFQHRIHWF 180
SIFNSFMMVI FLVGLVSMIL MRTLRKDYAR YSKEEEMDDM DRDLGDEYGW KQVHGDVFRP 240
SSHPLIFSSL IGSG 254 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro. 
Interpro
 IPR004240; EMP70. 
Pfam
 PF02990; EMP70 
SMART
  
PROSITE
  
PRINTS