| Tag | Content |
|---|
| CPLM ID | CPLM-011887 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar cation-transporting ATPase YPK9 |
Protein Synonyms/Alias | PARK9 homolog |
Gene Name | YPK9 |
Gene Synonyms/Alias | YOR291W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 672 | RTGFSTTKGSLVRSM | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Vacuolar transporter which plays a role in sequestration of divalent heavy metal ions. |
Sequence Annotation | ACT_SITE 781 781 4-aspartylphosphate intermediate (By
METAL 1187 1187 Magnesium (By similarity).
METAL 1191 1191 Magnesium (By similarity).
MOD_RES 95 95 Phosphothreonine.
MOD_RES 108 108 Phosphoserine.
MOD_RES 1117 1117 Phosphoserine.
MOD_RES 1120 1120 Phosphoserine. |
Keyword | ATP-binding; Complete proteome; Hydrolase; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Vacuole. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1472 AA |
Protein Sequence | MDIPSSNQIQ HGQRSERNRR MPRASFSSTA TTSTAATLTS AMVLDQNNSE PYAGATFEAV 60
PSSIVSFHHP HSFQSSNLPS PHSSGNLEQR GRRLTESEPL VLSSAEQSRS SSRNPSHFRF 120
FTQEQISNAE GASTLENTDY DMAWDATPAY EQDRIYGTGL SSRRSSIRSF SRASSLSNAK 180
SYGSFSKRGR SGSRAPQRLG ENSDTGFVYH SATHSSSSLS RYTTRERIPI ELESQTDEIL 240
EDESSTHSLE SSDSRRSASE NNRGSFSGHD DVHNQHSEYL KPDYHEKFYP QYAPNLHYQR 300
FYIAEEDLVI GIAAYQTSKF WYIIYNLCCF LTFGLVYLLT RWLPHLKVKL YGVKVPLAKA 360
EWVVIENEFG EFVIQPIDRQ WYNRPLSTVL PFENYPNPSY EPNDINLSHH HANEINPNVP 420
ILITFEYRYI KFIYSPLDDL FKTNNNWIDP DWVDLSTVSN GLTKGVQEDR ELAFGKNQIN 480
LRMKTTSEIL FNEVLHPFYV FQVFSIILWG IDEYYYYAAC IFLISVLSIF DSLNEQKKVS 540
RNLAEMSHFH CDVRVLRDKF WTTISSSELV PGDIYEVSDP NITILPCDSI LLSSDCIVNE 600
SMLTGESVPV SKFPATEETM YQLCDDFQST QISSFVSKSF LYNGTNIIRA RIAPGQTAAL 660
AMVVRTGFST TKGSLVRSMV FPKPTGFKFY RDSFKYIGFM SLIAIFGFCV SCVQFIKLGL 720
DKKTMILRAL DIITIVVPPA LPATLTIGTN FALSRLKEKG IFCISPTRLN ISGKIDVMCF 780
DKTGTLTEDG LDVLGVQISE PNGVRGQKFG ELLSDIRQVF PKFSLNDCSS PLDFKSRNFF 840
MSLLTCHSLR SVDGNLLGDP LDFKMFQFTG WSFEEDFQKR AFHSLYEGRH EDDVFPENSE 900
IIPAVVHPDS NNRENTFTDN DPHNFLGVVR SFEFLSELRR MSVIVKTNND DVYWSFTKGA 960
PEVISEICNK STLPADFEEV LRCYTHNGYR VIACAGKTLP KRTWLYSQKV SREEVESNLE 1020
FLGFIIFQNK LKKETSETLK SLQDANIRTI MCTGDNILTA ISVGREAGLI QCSRVYVPSI 1080
NDTPLHGEPV IVWRDVNEPD KILDTKTLKP VKLGNNSVES LRECNYTLAV SGDVFRLLFR 1140
DENEIPEEYL NEILLNSSIY ARMSPDEKHE LMIQLQKLDY TVGFCGDGAN DCGALKAADV 1200
GISLSEAEAS VAAPFTSKIF NISCVLDVIR EGRAALVTSF ACFQYMSLYS AIQFITITIL 1260
YSRGSNLGDF QFLYIDLLLI VPIAICMSWS KSYEKIDKKR PSANLVSPKI LVPLLISVFL 1320
VFLFQFIPWI IVQKMSWYIK PIVGGDDAVQ SSDNTVLFFV SNFQYILTAI VLSVGPPYRE 1380
PMSKNFEFIV DITVSIGASL LLMTLDTESY LGKMLQLTPI SNSFTMFIIV WVILNYYAQL 1440
YIPPSIKGWL KKKKSSKKYK LLIQEEMKLK EV 1472 |
Gene Ontology | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD. GO:0016021; C:integral to membrane; ISM:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006200; P:ATP catabolic process; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |