| Tag | Content |
|---|
| CPLM ID | CPLM-023367 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Leucine-rich repeat protein soc-2 homolog |
Protein Synonyms/Alias | Protein Sur-8 homolog; Protein soc-2 homolog |
Gene Name | Sur-8 |
Gene Synonyms/Alias | CG5407 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 142 | KPTTKKSKPIQADQD | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity). |
Sequence Annotation | REPEAT 161 182 LRR 1.
REPEAT 184 205 LRR 2.
REPEAT 207 228 LRR 3.
REPEAT 230 251 LRR 4.
REPEAT 253 274 LRR 5.
REPEAT 276 297 LRR 6.
REPEAT 299 320 LRR 7.
REPEAT 322 343 LRR 8.
REPEAT 345 367 LRR 9.
REPEAT 368 389 LRR 10.
REPEAT 392 413 LRR 11.
REPEAT 416 437 LRR 12.
REPEAT 440 461 LRR 13.
REPEAT 463 484 LRR 14.
REPEAT 486 507 LRR 15.
REPEAT 509 530 LRR 16.
REPEAT 532 553 LRR 17.
REPEAT 555 576 LRR 18.
REPEAT 578 600 LRR 19.
REPEAT 602 623 LRR 20. |
Keyword | Alternative splicing; Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 641 AA |
Protein Sequence | MNLCSSGATA STTSLSSTGQ AERSGGVPGG GAEGGGGSGN SGGGGKTSNG SAEAPTLCFA 60
GGSGTAGAIA GTEELSNANS PANGAGGATG STGSGQQPTG SNGHSHLHNE NNANMPPETR 120
PKMVTVKHPE SNKPKPTTKK SKPIQADQDV IKALQRCRDE GIKRLDLSKS SITVIPSTVK 180
ECVHLTELYL YSNKIGQLPP EIGCLVSLRN LALNENSLTS LPESLQNCSQ LKVLDLRHNK 240
LAEIPPVIYR LRSLTTLYLR FNRITAVADD LRQLVNLTML SLRENKIREL GSAIGALVNL 300
TTLDVSHNHL EHLPEDIGNC VNLSALDLQH NELLDIPDSI GNLKSLVRLG MRYNRLSSVP 360
ATLKNCKSMD EFNVEGNGIT QLPDGMLASL SGLTTITLSR NQFASYPTGG PAQFTNVYSI 420
NLEHNRIDKI PYGIFSRAKG LTKLNMKENM LTALPLDIGT WVNMVELNLA TNALQKLPDD 480
IMNLQNLEIL ILSNNMLKKI PNTIGNLRKL RILDLEENRI EVLPHEIGLL HELQRLILQT 540
NQITMLPRSI GHLGNLTHLS VSENNLQFLP EEIGSLESLE NLYINQNPGL EKLPFELALC 600
QNLKYLNIDK CPLSTIPPEI QAGGPSLVLQ WLKMHSPYRQ M 641 |
Gene Ontology | GO:0000164; C:protein phosphatase type 1 complex; IEA:InterPro. GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |