CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034698
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Abca8a 
Protein Synonyms/Alias
  
Gene Name
 Abca8a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
752LPLERTNKFPDLYRDacetylation[1]
1401ARLADALKLQDQLKSubiquitination[2]
1607EELDPSVKWKLLPQEubiquitination[2]
1609LDPSVKWKLLPQEEAubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1616 AA 
Protein Sequence
MVKREINVWQ QTWALLCKNL LRKKRLKRDT LWELLYTAFI LLCLSLFFEL HDVYEFSSLS 60
DVDLGRVDSF NDSTFAIAYT PVTPTTQEIM NRVSLVSYMT GREILAFPNK ENMTEFISKH 120
YDDAVGIIFS TAYSYHLKFM KGTRIPIIKE HQDHTAHCFR YEPAISCDLS AFWRHGFVAL 180
QAAINSAIIE VTTNHSVMEE MMSLTGKYIK IDSFIAQEGT TTDYFLFLCI IAFSPLTYYI 240
SAGVTRERKK MKAFMTVMGL RDSAFWLSWG LLYGVIVFIV TLFLTFVVYS VQFVFMTGFM 300
MIFSLFFFYG LSLISLSFLM SVLLKKSFLT DLVVFFLTVS CGSLGFAALY RYLPVSLEWL 360
LSLLSPFAFM LGMTQLLRLD YDLESSGHPT GNPNVVIATV FLLFFDGVFY LMLTFYFEKV 420
LPGEYGRRHP PLFFLKSSFW TGQNPADRTV LDNERDYEFP DDSFEPVSTD FHGKEVIRIR 480
NLTKEYIQRS KRTEALKDLT LDVYKGQITA ILGHSGAGKS TLLNVLSGLC VPTKGWVTIH 540
DNKLSEMTDL ESISKLTGVC PQCNVQFDFL TVRENLRLFA KIKGIQEVDN EVQRVLLALE 600
MKNIQNTLVQ NLSGGQKRKL TFGIAILGDP QIFLLDEPTA GLDPFSRHRV WNLLKERKAD 660
RVVLFSTQFM DEADILADRK VFISQGKLRC AGSSLFLKKK WGIGYHLSLQ LSETCVHERI 720
TSLVKQHIPD SKLSAESEGK LNYILPLERT NKFPDLYRDL ERCPDLGIEN YGVSVTTLTE 780
VFLKLEGKSA IDSVDIGETE DVQAGGTRGP GRLDGEQFVS LLNEMSKTKG GMALWWQQLC 840
AVTRLRFLKL KYRRKSIVIL ILILGIGLLH ILSANVHRLV NQSDYCWELS PHTYFLTPGQ 900
RPQMPLTNLL IINKTGEKID DFLHSLEQQN IALEVDAFGT RNGTEDSQYN GAIIVAGGEK 960
NYNFTLACNT KRLNCFPVLV DIVSNALLGL FTPSVHIQTD RSSFPEDTGY TQFYHLLYMF 1020
SWILLMACVP PYISMTSIDD YKNRAQFQLW ISGLSPSAYW FGHALFEIPV YSALILSVYI 1080
AFYFSAPPES MITTRDLFIQ ILYAGGYAMS VIFMMYVISF ICRKGRKNSG IWSLCFYIVS 1140
FISLCLMLFK FFEDTFLFSS IALIPVVTLV GCTLLHFQNH EFPEISLYPE RYYTYLFFLA 1200
PFFHFLIFLF ILRCLERKFG MKTMRMDPVF RISSRSDRVF NNPEEPEGED EDVSLERVRT 1260
ANALTSADFQ EKPVIIASCL RKEYKGKKKC FVLKGKKKIA TRNISLCVRK GEVVGLLGHN 1320
GAGKSTSIKM ITGEIKPSAG QVQLKGNSTG DTPEFLGYCP QENALWQHMT VREHLEIFAA 1380
IKGMSKSDAA VAIARLADAL KLQDQLKSPV KTLSEGVKRK LCFVLSILGN PSVVLLDEPS 1440
TGMDPEGQQQ MWQAIQATFA NTERGALLTT HYMAEAEAVC DRVAIMVSGK LRCIGSIQHL 1500
KSKFGKEYLL EMKVKTPTQV EPLNMEIMRL FPQAARQERY SSLMVYKLPR EDVQPLSQAF 1560
FKLETVKQSF DLEEYSLSQS TLEQVFLELS KEQELDDFEE ELDPSVKWKL LPQEEA 1616 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026082; ABC_A.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS