| Tag | Content |
|---|
| CPLM ID | CPLM-013512 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Puratrophin-1 |
Protein Synonyms/Alias | Pleckstrin homology domain-containing family G member 4; PH domain-containing family G member 4; Purkinje cell atrophy-associated protein 1 |
Gene Name | PLEKHG4 |
Gene Synonyms/Alias | PRTPHN1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 324 | GRELTWLKQEVPEVT | ubiquitination | [1] | | 430 | EQVRQGEKFLQPLTG | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi. |
Sequence Annotation | DOMAIN 732 908 DH.
DOMAIN 920 1027 PH.
MOD_RES 64 64 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; Guanine-nucleotide releasing factor; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1191 AA |
Protein Sequence | MERPLENGDE SPDSQGHATD WRFAVCSFRD AWEEEEPASQ MHVKDPGPPR PPAGATQDEE 60
LQGSPLSRKF QLPPAADESG DAQRGTVESS SVLSEGPGPS GVESLLCPMS SHLSLAQGTR 120
DVQGRAVLLL CAHSPAWLQS ECSSQELIRL LLYLRSIPRP EVQALGLTVL VDARICAPSS 180
SLFSGLSQLQ EAAPGAVYQV LLVGSTLLKE VPSGLQLEQL PSQSLLTHIP TAGLPTSLGG 240
GLPYCHQAWL DFRRRLEALL QNCQAACALL QGAIESVKAV PQPMEPGEVG QLLQQTEVLM 300
QQVLDSPWLA WLQCQGGREL TWLKQEVPEV TLSPDYRTAM DKADELYDRV DGLLHQLTLQ 360
SNQRIQALEL VQTLEARESG LHQIEVWLQQ VGWPALEEAG EPSLDMLLQA QGSFQELYQV 420
AQEQVRQGEK FLQPLTGWEA AELDPPGARF LALRAQLTEF SRALAQRCQR LADAERLFQL 480
FREALTWAEE GQRVLAELEQ ERPGVVLQQL QLHWTRHPDL PPAHFRKMWA LATGLGSEAI 540
RQECRWAWAR CQDTWLALDQ KLEASLKLPP VGSTASLCVS QVPAAPAHPP LRKAYSFDRN 600
LGQSLSEPAC HCHHAATIAA CRRPEAGGGA LPQASPTVPP PGSSDPRSLN RLQLVLAEMV 660
ATEREYVRAL EYTMENYFPE LDRPDVPQGL RGQRAHLFGN LEKLRDFHCH FFLRELEACT 720
RHPPRVAYAF LRHRVQFGMY ALYSKNKPRS DALMSSYGHT FFKDKQQALG DHLDLASYLL 780
KPIQRMGKYA LLLQELARAC GGPTQELSAL REAQSLVHFQ LRHGNDLLAM DAIQGCDVNL 840
KEQGQLVRQD EFVVRTGRHK SVRRIFLFEE LLLFSKPRHG PTGVDTFAYK RSFKMADLGL 900
TECCGNSNLR FEIWFRRRKA RDTFVLQASS LAIKQAWTAD ISHLLWRQAV HNKEVRMAEM 960
VSMGVGNKAF RDIAPSEEAI NDRTVNYVLK CREVRSRASI AVAPFDHDSL YLGASNSLPG 1020
DPASCSVLGS LNLHLYRDPA LLGLRCPLYP SFPEEAALEA EAELGGQPSL TAEDSEISSQ 1080
CPSASGSSGS DSSCVSGQAL GRGLEDLPCV 1110 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |