CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038481
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Unconventional myosin-X 
Protein Synonyms/Alias
  
Gene Name
 Myo10 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
905LPSRGILKYLKFHLKacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1316 AA 
Protein Sequence
MVIRAHILGY LARKQYRKVL CGVVTIQKNY RAFLARKKFL HLKKAAIVFQ KQLRGQLARR 60
VYRQLLAEKR ELEEKKRREE EKKREEEERE RERAQREADL LRAHQEAETR RQQELEALQK 120
SQREADLTRE LEKQRENKQV EEILRLEKEI EDLQRMKERQ ELSLTEASLQ KLQQLRDEEL 180
RRLEDEACRA AQEFLESLNF DEIDECVRNI ERSLSVGSEI SGEELSELAE SASGEKPNFN 240
FSQPYPAEEE VDEGFEADDD AFKDSPNPSE HGHSDQRTSG IRTSDDSSEE DPYMNYTVVP 300
TSPSADSTVL LAASMQDSAS LHNSSSGEST YCMPQNNGDL PSPDGDYDYD QDDYEDGAIT 360
SGSSVTFSNS YGSQWSPDYR YSVGTYNSSG AYRFSSEGAQ SSFEDSEEDF DSRFDTDDEL 420
SYRRDSVYSC VTLPYFHSFL YMKGGLMNSW KRRWCVLKDE TFLWFRSKQE ALKQGWLHKK 480
GGGSSTLSRR NWKKRWFVLR QSKLMYFEND SEEKLKGTVE VRTAKEIIDN TSKENGIDII 540
LADRTFHLIA ESPEDASQWF SVLSQVHSST DQEIREMHDE QANPQNAVGT LDVGLIDSVC 600
ASDSPDRPNS FVIITANRVL HCNADTPEEM HHWITLLQRS KGDTRVEGQE FIVRGWLHKE 660
VKNSPKMSSL KLKKRWFVLT HNSLDYYKSS EKNALKLGTL VLNSLCSVVP PDEKIFKETG 720
YWNVTVYGRK HCYRLYTKLL NEATRWSSAI QNVTDTKAPI DTPTQQLIQD IKENCLNSDV 780
VEQIYKRNPI LRYTHHPLHS PLLPLPYGDI NLNLLKDKGY TTLQDEAIKI FNSLQQLESM 840
SDPIPIIQGI LQTGHDLRPL RDELYCQLIK QTNKVPHPGS VGNLYSWQIL TCLSCTFLPS 900
RGILKYLKFH LKRIREQFPG TEMEKYALFI YESLKKTKCR EFVPSRDEIE ALIHRQEMTS 960
TVYCHGGGSC KITINSHTTA GEVVEKLIRG LAMEDSRNMF ALFEYNGQVD KAIESRTIVA 1020
DVLAKFEKLA ATSEAGDAPW KFYFKLYCFL DTDSMPKDSV EFAFMFEQAH EAVIHGHHPA 1080
PEESLQVLAA LRLQYLQGDY TPHTSIPPLE EVYSVQRLRA RISQSTKTFT PYERLEKRRT 1140
SFLEGTLRRS FRTGSVVRQK AEEEQMLDMW IKEEVCSART SIIDKWKKLQ GMNQEQAMAK 1200
YMALIKEWPG YGSTLFDVEC KEGGFPQELW LGVSADAVSV YKRGEGKPLE VFQYEHILSF 1260
GAPLANTYKI VVDERELLFE TSEVVDVAKL MKAYISMIVK KRYSTTRSVS SQGSSR 1316 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005856; C:cytoskeleton; IEA:InterPro.
 GO:0030175; C:filopodium; IDA:MGI.
 GO:0043005; C:neuron projection; IDA:MGI.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0048870; P:cell motility; IC:MGI.
 GO:0022409; P:positive regulation of cell-cell adhesion; IGI:MGI.
 GO:0008360; P:regulation of cell shape; IEA:Compara.
 GO:0051489; P:regulation of filopodium assembly; IEA:Compara.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR019749; Band_41_domain.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR000299; FERM_domain.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR000857; MyTH4_dom.
 IPR027417; P-loop_NTPase.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00373; FERM_M
 PF00612; IQ
 PF00784; MyTH4
 PF00169; PH 
SMART
 SM00295; B41
 SM00015; IQ
 SM00139; MyTH4
 SM00233; PH 
PROSITE
 PS50057; FERM_3
 PS50096; IQ
 PS51016; MYTH4
 PS50003; PH_DOMAIN 
PRINTS