UniProt Accession

 B0QYL9_HUMAN; B0QYL9 

Genbank Protein ID

 AL031587 

Genbank Nucleotide ID

  

Protein Name

 DNA-directed RNA polymerases I, II, and III subunit RPABC2 

Protein Synonyms/Alias

  

Gene Name

 POLR2F 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
59	ITTPYMTKYERARVL	ubiquitination	[1, 2]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 158 AA 

Protein Sequence

Gene Ontology

 GO:0030880; C:RNA polymerase complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR020708; DNA-dir_RNA_polK_14-18kDa_CS.
 IPR006110; RNA_poly_omega/K/RPABC2.
 IPR006111; RNAP_K/Rpb6.
 IPR012293; RNAP_RPB6_omega. 

Pfam

 PF01192; RNA_pol_Rpb6 

SMART

  

PROSITE

 PS01111; RNA_POL_K_14KD 

PRINTS