| Tag | Content |
|---|
| CPLM ID | CPLM-019893 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | RNA-binding protein 10 |
Protein Synonyms/Alias | RNA-binding motif protein 10 |
Gene Name | Rbm10 |
Gene Synonyms/Alias | Kiaa0122 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 872 | MLQAMGWKEGSGLGR | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Not known. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). |
Sequence Annotation | DOMAIN 129 209 RRM 1.
DOMAIN 300 384 RRM 2.
DOMAIN 858 904 G-patch.
ZN_FING 212 242 RanBP2-type.
ZN_FING 759 784 C2H2-type; atypical.
MOD_RES 61 61 Phosphoserine (By similarity).
MOD_RES 89 89 Phosphoserine (By similarity).
MOD_RES 383 383 N6-acetyllysine (By similarity).
MOD_RES 718 718 Phosphoserine (By similarity).
MOD_RES 723 723 Phosphoserine (By similarity).
MOD_RES 733 733 Phosphoserine.
MOD_RES 736 736 Phosphoserine.
MOD_RES 738 738 Phosphoserine.
MOD_RES 781 781 Phosphoserine (By similarity).
MOD_RES 797 797 Phosphoserine (By similarity). |
Keyword | Acetylation; Alternative splicing; Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 930 AA |
Protein Sequence | MEYERRGGRG DRTGRYGATD RSQDDSGENR SRDHDYRDMD YRSYPREYGS QEGKHEYDDS 60
SEEQSAEDSY EASPGSETQR RRRRRHRHSP TGPPGFPRDG DYRDQDYRTE QGEEEEEEDE 120
EEEEEKASNI VMLRMLPQAA TEDDIRGQLQ SHGVQAREVR LMRNKSSGQS RGFAFVEFSH 180
LQDATRWMEA NQHSLNILGQ KVSMHYSDPK PKINEDWLCN KCGVQNFKRR EKCFKCGVPK 240
SEAEQKLPLG TRLDQQALPL GGRELSQGLL PLPQPYQAQG VLTSQALSQG SEPSSENAND 300
TIILRNLNPH STMDSILGAL APYAVLSSSN VRVIKDKQTQ LNRGFAFIQL STIVEAAQLL 360
QILQALHPPL TIDGKTINVE FAKGSKRDMA SNEGSRINAA SVASTAIAAA QWAISQASQG 420
GESAWAAPEE PPVDYSYYQQ DEGYGSSQGT DSLYAHGYLK NSKGPGMTGT KGDPAGTGPE 480
ASLEAGADSV SLQAFSRAQP GAAPGLYQQS AEGSSGQSTA TNSQSYTIIS PAVLKAELQS 540
PTQPSSSAFP PATSPTAPEA YSQYPVPDVS TYQYDETSGY YYDPQTGLYY DPNSQYYYNA 600
QSQQYLYWDG ERRTYIPALE QSADGHKDTG ASSKEGKEKK EKHKTKTAQQ IAKDMERWAR 660
SLNKQKENFK NSFQPISALR DDERRESATA DAGYAILEKK GALAERQHTS MDLPKLASDD 720
RPSPPRGLVA AYSGESDSEE EQERGGPERE EKLTDWQKLA CLLCRRQFPS KEALIRHQQL 780
SGLHKQNLEI HRRAHLSENE LEALEKNDME QMKYRDRAAE RREKYGIPEP PEPKRRKYGG 840
ISTASVDFEQ PTRDGLGSDN IGSRMLQAMG WKEGSGLGRK KQGIVTPIEA QTRVRGSGLG 900
ARGSSYGVTS TESYKETLHK TMVTRFNEAQ 930 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0000166; F:nucleotide binding; IEA:InterPro. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:MGI. GO:0008285; P:negative regulation of cell proliferation; IDA:MGI. GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |