Tag | Content |
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CPLM ID | CPLM-016179 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 554 |
Protein Synonyms/Alias | |
Gene Name | ZNF554 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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406 | QRIHTGEKPYKCEDC | ubiquitination | [1] | 409 | HTGEKPYKCEDCGKS | ubiquitination | [1] |
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Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 45 148 KRAB. ZN_FING 271 292 C2H2-type 1; degenerate. ZN_FING 324 346 C2H2-type 2. ZN_FING 352 374 C2H2-type 3. ZN_FING 380 402 C2H2-type 4. ZN_FING 408 430 C2H2-type 5. ZN_FING 436 458 C2H2-type 6. ZN_FING 464 486 C2H2-type 7. ZN_FING 492 514 C2H2-type 8. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 538 AA |
Protein Sequence | MVTCAHLGRR ARLPAAQPSA CPGTCFSQEE RMAAGYLPRW SQELVTFEDV SMDFSQEEWE 60 LLEPAQKNLY REVMLENYRN VVSLEALKNQ CTDVGIKEGP LSPAQTSQVT SLSSWTGYLL 120 FQPVASSHLE QREALWIEEK GTPQASCSDW MTVLRNQDST YKKVALQEEP ASGINMIKLI 180 REDGGWKQLE DSHEDPQGLL SQKASLHVVA VPQEKATAWH GFGENGNLSP ALVLSQGSSK 240 GNHLCGSELD ITSLASDSVL NHHQLGYADR RPCESNECGN AIRQNSHFIQ HGGKMFVYLE 300 NGQSLNHGMA LTIHNKINTA EKPFECHQCG KVFNRRHSLS EHQRIHTGEK PYECQECGRA 360 FTHSSTLTRH LRTHTGEKPY GCGECGKAFN RISSLTQHQR IHTGEKPYKC EDCGKSFCQS 420 SYLILHKRTH TGEKPYECSE CGKAFSDRSS LNQHERTHTG ENPYECKQCG RAFSQRSSLV 480 RHERTHTGEK PYRCQECGKA FSQSSSLVTH QKTHSSQKTY KIIDCGKAFY QNRHLIGY 538 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |