CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kynurenine 3-monooxygenase 
Protein Synonyms/Alias
  
Gene Name
 Kmo 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
105LEDQIVSKGVPMKARubiquitination[1]
129SAIPYGNKSQYILSIacetylation[2]
129SAIPYGNKSQYILSIubiquitination[1]
143ISRENLNKDLLTAVEacetylation[2]
143ISRENLNKDLLTAVEubiquitination[1]
162AKVHFGHKLSKCIPEacetylation[2, 3]
165HFGHKLSKCIPEEGVacetylation[2, 3]
165HFGHKLSKCIPEEGVubiquitination[1]
180LTVLGPDKVPRDVTCacetylation[2]
206TVRAHLMKKPRFDYTacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 255 AA 
Protein Sequence
MKVTVAHLSL CLNSTNMDGA GWRQTTTSYQ TLERLQVSLS PLPTKVGALN ACFLAKRNFQ 60
VDVYEAREDI RVAKSARGRS INLALSYRGR QALKAIGLED QIVSKGVPMK ARMIHSLSGK 120
KSAIPYGNKS QYILSISREN LNKDLLTAVE SYANAKVHFG HKLSKCIPEE GVLTVLGPDK 180
VPRDVTCDLV VGCDGAYSTV RAHLMKKPRF DYTQQYIPHG YMELTIPPKN GEKCLYDDRP 240
SKHGQIFHMH LVHAL 255 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI. 
Interpro
 IPR002938; mOase_FAD-bd. 
Pfam
 PF01494; FAD_binding_3 
SMART
  
PROSITE
  
PRINTS