| Tag | Content |
|---|
| CPLM ID | CPLM-002428 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Methyl-accepting chemotaxis protein II |
Protein Synonyms/Alias | MCP-II; Aspartate chemoreceptor protein |
Gene Name | tar |
Gene Synonyms/Alias | cheM; b1886; JW1875 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 340 | DTAQHGGKVVDGVVK | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Receptor for the attractant L-aspartate and related amino and dicarboxylic acids. Tar also mediates taxis to the attractant maltose via an interaction with the periplasmic maltose binding protein. Tar mediates taxis away from the repellents cobalt and nickel. |
Sequence Annotation | DOMAIN 214 266 HAMP.
DOMAIN 271 500 Methyl-accepting transducer.
REGION 64 73 The 3 Arg may form a positively charged
MOD_RES 295 295 Glutamate methyl ester (Gln).
MOD_RES 302 302 Glutamate methyl ester (Glu).
MOD_RES 309 309 Glutamate methyl ester (Gln).
MOD_RES 491 491 Glutamate methyl ester (Glu). |
Keyword | 3D-structure; Cell inner membrane; Cell membrane; Chemotaxis; Complete proteome; Membrane; Methylation; Reference proteome; Transducer; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 553 AA |
Protein Sequence | MINRIRVVTL LVMVLGVFAL LQLISGSLFF SSLHHSQKSF VVSNQLREQQ GELTSTWDLM 60
LQTRINLSRS AVRMMMDSSN QQSNAKVELL DSARKTLAQA ATHYKKFKSM APLPEMVATS 120
RNIDEKYKNY YTALTELIDY LDYGNTGAYF AQPTQGMQNA MGEAFAQYAL SSEKLYRDIV 180
TDNADDYRFA QWQLAVIALV VVLILLVAWY GIRRMLLTPL AKIIAHIREI AGGNLANTLT 240
IDGRSEMGDL AQSVSHMQRS LTDTVTHVRE GSDAIYAGTR EIAAGNTDLS SRTEQQASAL 300
EETAASMEQL TATVKQNADN ARQASQLAQS ASDTAQHGGK VVDGVVKTMH EIADSSKKIA 360
DIISVIDGIA FQTNILALNA AVEAARAGEQ GRGFAVVAGE VRNLASRSAQ AAKEIKALIE 420
DSVSRVDTGS VLVESAGETM NNIVNAVTRV TDIMGEIASA SDEQSRGIDQ VALAVSEMDR 480
VTQQNASLVQ ESAAAAAALE EQASRLTQAV SAFRLAASPL TNKPQTPSRP ASEQPPAQPR 540
LRIAEQDPNW ETF 553 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |