CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021937
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleolar protein of 40 kDa 
Protein Synonyms/Alias
 pNO40; Pnn-interacting nucleolar protein; Putative S1 RNA-binding domain protein; PS1D protein; Zinc finger CCHC domain-containing protein 17 
Gene Name
 ZCCHC17 
Gene Synonyms/Alias
 PS1D; HSPC243; HSPC251; LDC4 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
144GCKGHFAKDCFMQPGacetylation[1]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861
Functional Description
  
Sequence Annotation
 DOMAIN 16 88 S1 motif.
 ZN_FING 131 148 CCHC-type.
 MOD_RES 114 114 Phosphoserine.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 241 AA 
Protein Sequence
MNSGRPETME NLPALYTIFQ GEVAMVTDYG AFIKIPGCRK QGLVHRTHMS SCRVDKPSEI 60
VDVGDKVWVK LIGREMKNDR IKVSLSMKVV NQGTGKDLDP NNVIIEQEER RRRSFQDYTG 120
QKITLEAVLN TTCKKCGCKG HFAKDCFMQP GGTKYSLIPD EEEEKEEAKS AEFEKPDPTR 180
NPSRKRKKEK KKKKHRDRKS SDSDSSDSES DTGKRARHTS KDSKAAKKKK KKKKHKKKHK 240
E 241 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR012340; NA-bd_OB-fold.
 IPR003029; Rbsml_prot_S1_RNA-bd_dom.
 IPR022967; RNA-binding_domain_S1.
 IPR001878; Znf_CCHC. 
Pfam
 PF00575; S1 
SMART
 SM00316; S1
 SM00343; ZnF_C2HC 
PROSITE
 PS50126; S1
 PS50158; ZF_CCHC 
PRINTS