CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032468
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mismatch repair endonuclease PMS2 
Protein Synonyms/Alias
 Postmeiotic segregation increased 2 (S. cerevisiae); Postmeiotic segregation increased 2 (S. cerevisiae), isoform CRA_d 
Gene Name
 Pms2 
Gene Synonyms/Alias
 mCG_17957 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
431AFSLHPTKEIKSRGPacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 859 AA 
Protein Sequence
MEQTEGVSTE CAKAIKPIDG KSVHQICSGQ VVLSLSTAVK ELIENSVDAG ATTIDLRLKD 60
YGVDLIEVSD NGCGVEEENF EGLALKHHTS KIQEFADLTQ VETFGFRGEA LSSLCALSDV 120
TISTCHGSAS VGTRLVFDHN GKITQKTPYP RPKGTTVSVQ HLFYTLPVRY KEFQRNIKKE 180
YAKMVQVLQA YCIISAGVRV SCTNQLGQGK RQPVVCTSGS SGMKENIGSV FGQKQLQSLI 240
PFVQLPPSDA VCEEYGLSTS RTPQNLFYVS GFISQCTHGA GRSATDRQFF FINQRPCDPA 300
KVSKLVNEVY HMYNRHQYPF VVLNVSVDSE CVDINVTPDK RQILLQEEKL LLAVLKTSLI 360
GMFDSDANKL NVNQQPLLDV EGNLVKLHTA ELEKPVPGKQ DNSPSLKSTA DEKRVASISR 420
LREAFSLHPT KEIKSRGPET AELTRSFPSE KRGVLSSYPS DVISYRGLRG SQDKLVSPTD 480
SPGDCMDREK IEKDSGLSST SAGSEEGFST PEVASSFSSD YNVSSPEDRP SQETINCGDL 540
DCRPPGTGQS LKPEDHGYQC KALPLARLSP TNAKRFKTEE RPSNVNISQR LPGPQSTSAA 600
EVDVAIKMNK RIVLLEFSLS SLAKRMKQLQ HLKAQNKHEL SYRKFRAKIC PGENQAAEDE 660
LRKEISKSMF AEMEILGQFN LGFIVTKLKE DLFLVDQHAA DEKYNFEMLQ QHTVLQAQRL 720
ITPQTLNLTA VNEAVLIENL EIFRKNGFDF VIDEDAPVTE RAKLISLPTS KNWTFGPQDI 780
DELIFMLSDS PGVMCRPSRV RQMFASRACR KSVMIGTALN ASEMKKLITH MGEMDHPWNC 840
PHGRPTMRHV ANLDVISQN 859 
Gene Ontology
 GO:0032389; C:MutLalpha complex; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0016887; F:ATPase activity; IBA:RefGenome.
 GO:0032407; F:MutSalpha complex binding; IBA:RefGenome.
 GO:0032138; F:single base insertion or deletion binding; IEA:Compara.
 GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
 GO:0006298; P:mismatch repair; IMP:MGI.
 GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI.
 GO:0016447; P:somatic recombination of immunoglobulin gene segments; IMP:MGI. 
Interpro
 IPR002099; DNA_mismatch_repair.
 IPR013507; DNA_mismatch_repair_C.
 IPR014762; DNA_mismatch_repair_CS.
 IPR014763; DNA_mismatch_repair_N.
 IPR003594; HATPase_ATP-bd.
 IPR014790; MutL_C.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 
Pfam
 PF01119; DNA_mis_repair
 PF08676; MutL_C 
SMART
 SM00387; HATPase_c
 SM00853; MutL_C 
PROSITE
 PS00058; DNA_MISMATCH_REPAIR_1 
PRINTS