Tag | Content |
---|
CPLM ID | CPLM-015636 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Xin actin-binding repeat-containing protein 2 |
Protein Synonyms/Alias | Beta-xin; Cardiomyopathy-associated protein 3; L-NAME-induced actin cytoskeletal protein |
Gene Name | Xirp2 |
Gene Synonyms/Alias | Cmya3; Xin2 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
---|
1109 | HEVTTVKKEETIHGD | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Protects actin filaments from depolymerization (By similarity). |
Sequence Annotation | REPEAT 306 321 Xin 1. REPEAT 341 356 Xin 2. REPEAT 381 396 Xin 3. REPEAT 418 433 Xin 4. REPEAT 456 471 Xin 5. REPEAT 496 511 Xin 6. REPEAT 534 549 Xin 7. REPEAT 572 587 Xin 8. REPEAT 606 621 Xin 9. REPEAT 640 655 Xin 10. REPEAT 677 692 Xin 11. REPEAT 713 728 Xin 12. REPEAT 744 759 Xin 13. REPEAT 782 797 Xin 14. REPEAT 820 835 Xin 15. REPEAT 859 874 Xin 16. REPEAT 892 907 Xin 17. REPEAT 930 945 Xin 18. REPEAT 965 980 Xin 19. REPEAT 1004 1019 Xin 20. REPEAT 1040 1055 Xin 21. REPEAT 1077 1092 Xin 22. REPEAT 1115 1130 Xin 23. REPEAT 1152 1167 Xin 24. REPEAT 1186 1201 Xin 25. REPEAT 1217 1232 Xin 26. REPEAT 1254 1269 Xin 27. REPEAT 1289 1304 Xin 28. MOD_RES 1930 1930 Phosphothreonine. MOD_RES 1935 1935 Phosphoserine. |
Keyword | Actin-binding; Cell junction; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3302 AA |
Protein Sequence | MARYQAAVSR GDTRSFSANV MEESDLCTVP GGLAKMKRQF EKDEMTSTCN AFSEYQYQHE 60 SRSEQEAIHN RQEIRRNEEE VSKGHRTDVF KAEMMSHLEK HTEETNQASQ FRQYVQETVI 120 DTPEDEEIPK VSTKILKEQF EKTAQENFLY SDKETTTPAK CIKIENDSEE TLKPSSAMGT 180 SSYTSARQSK ETSTSSYSNH SLTSTILAQE KGTPSGKMEE FPPPPPDVFQ TPMDVTAFSQ 240 SPEFPSPPRR LPMPRDVYSK QRNLYELNRL YRHIHPELRK NLEKDYISEV SEIVSSHINS 300 GNSISAGVQQ ARYVFENTND SSQKDLSSER ENLEWDEILK GEVQSIRWIF ENQPLDSINQ 360 GFTDEAYTSK GIADQELIAG GDVKYTTWMF ETQPIDALGV PSAGTEENTE KIPELAKGDV 420 CTARWMFETR PLDSMNKMHE WEDETASTFI KDITGGDVKT VRYMFETQQL DQLGQLHSVD 480 EMNLLQLRSE LKEIKGNVKR SIKCFETQPL YVIRDGSGQM LEIKTVQRED IEKGDVRTAR 540 WMFETQPLDT IKQDITEIKV VRGISMEENV KGEVGRARWL FETQPLEKIK EESGEAVLKT 600 EAVVGIDVSK KCWMFETQPL DTLKQSPDTE SVSPEERIGG DVKTTKHLLE TLPIEALKDS 660 PDVGKLQKIT ASEEEKGDVK HQKWVFETQR LEDIREDKKE YTQTVKLEAV DRGHVKNYTH 720 IFESNNLIKV DASHQIEVEG VTRGTVELNK SLFETTPLYA IQDHLGKYHQ VKTVQQEEIV 780 RGDVRSCRWL FETRPIDQFD ESLHKFQIIR GISAQEIQAG NVKSARWLFE TQPLDSIKYF 840 SNVEETDSKT EQSTDIVKGD VKTCKWLFET QPMESLYEKA SLMTNSEDIH KGDVRTCMWL 900 FETQPLDAIK NDSEATVKLQ TVKQEEIQGG DVRTACLLFE TENLDNIQGG EGKETKPVEM 960 DIESGDVSGM KYKFENQSLD SISCSSENVL NKIKTLKIED IQKGNVLNCR WLFENQPIDM 1020 IKENQEGDGL VKTVTDIQGG DVRKGCFIFE TFSLDEIKDE SDVISTRQTN TEEVIKGDVK 1080 SYKMLFETQP LYAIQDQEGF YHEVTTVKKE ETIHGDVRGT RWLFETKPLD SINASEDVYI 1140 IKSVTQEDIQ KGDVSSVRYR FETQPLDMIS DKSHNIMPTI DHIQGGNVQM NKQLFESEGG 1200 DKKNYVRTVS INEIQKGNVK TSTWLFETHS IDELGEVSTY ENIKTVTQED VQKGDVKQAV 1260 WLFENQTLDS IKELDESDTK ITKEEIPPSD VKTTTWLFET TPIHEFNETR IEKEEIIGKS 1320 IKETLEDLYS QRVVEAPGII IEADEVGDVR MAKYKLMNQR TPEIQKEEVI RADLGNIMMN 1380 LLSQRDCTKK EIFISEEEKG NVNFTKTQLL NRSMEFHAEK EEIVRGDVKQ AIQKLFSEER 1440 CAKRGILIQE DEKGDVNMTI YCLLHENAGD KTKREDILGG DVRRTIHNLL SSASNDKISE 1500 RTKIDASERG NVQFFTTCIE TGALDYLKQL QTGSNETLTA RKQEGEEEII GGDVEGTKFL 1560 LKKRQSSIER TVSETDIIPG DVRNTVKVFM TEPQSASFKT AKEEIVKGDL KSTLNSLNQA 1620 MNQKVVAKTE DIMKDDKAAI LKSLKESGGR QKEHKQSASI SSDIGQAIEC LEKATNTRTE 1680 ILKKELILDD LKTSLRSLKE EQYSFKEVGK QGMVKDVLGF SERQELGIHP AAVQREKKSL 1740 LQPVPGPCEP AIRQQAGPGP LDEATQKSCH RSLTEERTEA NLPKAPKGTV KIVIDREQNN 1800 DALEKSLRKM SNSEHRAMKN VLDMGDRRGV WTESKECLCS DDHMSKYVSA SMSRKKSLKT 1860 KESENVRESK DDVSSTQSVD KTFRKQQTQN CELGKDHQKS QFQDSYAKNQ KNTQNISMSA 1920 ETQSYRPDPT QHPVSNPAGE TLEMTRDFQK QALIRQEKQN SNKDMRKNDM GLQPLPVGKD 1980 AHSAPGVTVS GKNHKRTQAP DKKQRIDVCL ESQDFLMKTN TSKELKMAME RSFNPVNLYP 2040 DCGVKENEDA LPPPSPPPPP PSNASSEIEF PLPPPPPIML LPEKNEFPPS SPTEKSRAEL 2100 ESLPTLPLPP PPGDEKSDQE CLPTSLPPPP PTAPSQPAHL LSSSVLEHHS EAFLQQYSRK 2160 ETLDSHQLHS QAKILTGKSP PPTLPKPKLP ERIKAKMSQD SPSGELERSL SDVEIKTTLS 2220 KDQKSSLVAE SREHTEAKQE VFRKSLGRKQ LSISSANSLS QTVPEIPAPK EKQTAPLVKS 2280 HSFPSGSEQQ SPKPYMRKFK TPLMIAEEKY RQQREELEKQ RRESSCHSII KTETQHRSLS 2340 EKEKETELQK AAEAMSTPRK DSDFTRAQPN LEPKSKAVIA SECSESQLST ASALTVATER 2400 LQHVLAASDD KLTLRREGTQ NSSDTLQSKT ACEINQSHKE CRTEQTFEQH VEKLPFPQTK 2460 PISPSFKVKT IRLPALDHTL TETDLSSERR VKQSEIDVQT STKEMNKEIK KTEVSTQCDN 2520 KQSVAEKYFQ LPKTEKRVTV QMPKDYAAKS HQSKLQTVPK KHGGLGEFDR GNVLGREGKN 2580 QDSSMSSTKE SRVIVERKQE HLQDQSVPRL VQQKIIGESL DSRVQNFQQT QTQTSRIEHK 2640 ELSQPYSEKK CLRDKDKQQK QVSSNTDDSK QEITQKQSSF SSVRESQQDG EKCAINILEF 2700 LRKREELQQI LSRVKQFEAD SNKSGLKTFQ TLLNIAPVWL ISEEKREYGV RVAMENNLEK 2760 VKEEIIHIKT QAEEMLVHCE HVIRTAMMAS QTGKQKDKPT NLNEMPLKVS NVNLSSHKGT 2820 EQKESKIVEE KLASRQVATH SEAATHNPAK TYQEAKGDDS KMAPPSLKTR PPSPTFITIE 2880 STARRAETST KSELSQSPKN NSCVEPLPRR PMEHTSRLPR TSTSPSPPRS RSEQLVRLKD 2940 TTARLAKGTI PCSPGTPVPV VEKRSEVVMS PATLRRQIKI ESRGGDSPPT ITIPVSVNHH 3000 VVSGSFRESV DAQEAVKKTE KTETYVHKDK KNSVSSAMPE TESYDAVEII RKVEGPHLSE 3060 HRERFEATNQ TVQMAEHFLN GHENEVNRWF REFENGPVFG AKTERRAYAN GEINHNMKQE 3120 SHTFCKEEFG LESSETANFT GFSYRHPREH RAKAPATQPR VHSEARALNE HFLSVDAFDS 3180 QIVESQVATS SSRSSEAGRS GFDFKHAPPT YEDVIAGHIL DIADSPTNLR RNFQKTWQES 3240 ERVFKSVGYE TSDAHATEMS RAFQEELAFL SETVGPRQGN LHNLSKDGLS NGVPRSRPAE 3300 FS 3302 |
Gene Ontology | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell. GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |