CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013966
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UPF0668 protein C10orf76 
Protein Synonyms/Alias
  
Gene Name
 C10orf76 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
62NLEYLEGKLESLDGEubiquitination[1]
383SIVMQDTKDEHRLHSubiquitination[1]
580STNAGQWKEAASKVTubiquitination[1]
635NYDTLTLKLQDGLDQubiquitination[1, 2]
657HKEAAFFKELVRSISubiquitination[1, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 689 AA 
Protein Sequence
MAQVEKRGGL LRKSSASKKP LKEKVVLMYD EIFMTEDPSK CSPRFWEELF LMKVNLEYLE 60
GKLESLDGEE LMKIKDNINC LFQHCIQALG EEHPIRVVNA LQTLCALIRG VHQKNKSTSG 120
FDIINMLMGF DKAELCMKNL MESLDSLLCA EGSESLKSLC LKLLLCLVTV TDNISQNTIL 180
EYVMINSIFE AILQILSHPP SRREHGYDAV VLLALLVNYR KYESVNPYIV KLSIVDDEAT 240
LNGMGLVIAQ ALSEYNRQYK DKEEEHQSGF FSALTNMVGS MFIADAHEKI SVQTNEAILL 300
ALYEAVHLNR NFITVLAQSH PEMGLVTTPV SPAPTTPVTP LGTTPPSSDV ISSVELPLDA 360
DVQTSNLLIT FLKYSSIVMQ DTKDEHRLHS GKLCLIILTC IAEDQYANAF LHDDNMNFRV 420
NLHRMPMRHR KKAADKNLPC RPLVCAVLDL MVEFIVTHMM KEFPMDLYIR CIQVVHKLLC 480
YQKKCRVRLH YTWRELWSAL INLLKFLMSN ETVLLAKHNI FTLALMIVNL FNMFITYGDT 540
FLPTPSSYDE LYYEIIRMHQ SFDNLYSMVL RLSTNAGQWK EAASKVTHAL VNIRAIINHF 600
NPKIESYAAV NHISQLSEEQ VLEVVRANYD TLTLKLQDGL DQYERYSEQH KEAAFFKELV 660
RSISTNVRRN LAFHTLSQEV LLKEFSTIS 689 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR013636; DUF1741. 
Pfam
 PF08427; DUF1741 
SMART
  
PROSITE
  
PRINTS