| Tag | Content |
|---|
| CPLM ID | CPLM-022177 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | GTPase IMAP family member 4 |
Protein Synonyms/Alias | Immunity-associated nucleotide 1 protein; IAN-1; hIAN1; Immunity-associated protein 4 |
Gene Name | GIMAP4 |
Gene Synonyms/Alias | IAN1; IMAP4; MSTP062 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 262 | IREEYEEKIRKLEDK | acetylation | [1] |
|
Reference | [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Science. 2009 Aug 14;325(5942):834-40. [ PMID: 19608861] |
Functional Description | May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium. |
Sequence Annotation | NP_BIND 37 45 GTP.
NP_BIND 155 157 GTP.
BINDING 58 58 GTP.
BINDING 191 191 GTP. |
Keyword | 3D-structure; Coiled coil; Complete proteome; Cytoplasm; GTP-binding; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 329 AA |
Protein Sequence | MAAQYGSMSF NPSTPGASYG PGRQEPRNSQ LRIVLVGKTG AGKSATGNSI LGRKVFHSGT 60
AAKSITKKCE KRSSSWKETE LVVVDTPGIF DTEVPNAETS KEIIRCILLT SPGPHALLLV 120
VPLGRYTEEE HKATEKILKM FGERARSFMI LIFTRKDDLG DTNLHDYLRE APEDIQDLMD 180
IFGDRYCALN NKATGAEQEA QRAQLLGLIQ RVVRENKEGC YTNRMYQRAE EEIQKQTQAM 240
QELHRVELER EKARIREEYE EKIRKLEDKV EQEKRKKQME KKLAEQEAHY AVRQQRARTE 300
VESKDGILEL IMTALQIASF ILLRLFAED 329 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |