CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018133
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UBX domain-containing protein 4 
Protein Synonyms/Alias
 Erasin; UBX domain-containing protein 2 
Gene Name
 Ubxn4 
Gene Synonyms/Alias
 Ubxd2; Ubxdc1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
57SNNFVAIKIDTKSEAubiquitination[1]
108ELVTRIHKVQQMHSSubiquitination[1]
116VQQMHSSKGEASVTNubiquitination[1]
268RAARERIKQQIALDRubiquitination[1]
299KAAALLTKQAGTEVKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Involved in endoplasmic reticulum-associated protein degradation (ERAD) (By similarity). 
Sequence Annotation
 DOMAIN 313 391 UBX.
 MOD_RES 487 487 Phosphothreonine (By similarity).  
Keyword
 3D-structure; Complete proteome; Endoplasmic reticulum; Membrane; Nucleus; Phosphoprotein; Reference proteome; Unfolded protein response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 506 AA 
Protein Sequence
MLWFQGAIPA AIASAKRSGA VFVVFVAGDD EQSIQMAASW EDEKVTQASS NNFVAIKIDT 60
KSEACLQFSQ IYPVVCVPSS FFIGDSGIPL EVIAGSVSAD ELVTRIHKVQ QMHSSKGEAS 120
VTNDNQSESS VSTPSASFEP DVCENPESKN TELCETPATS DIKSDTATGG ECTGHDSHSQ 180
EPHGCSNQRP AEDLTVRVER LTKKLEERRE EKRKEEAQRE IKKEIERRKT GKEMLDYKRK 240
QEEELTKRML EERSREKAED RAARERIKQQ IALDRAERAA RFAKTKEAEA AKAAALLTKQ 300
AGTEVKREST ARDRSTIARI QFRLPDGSSF TNQFPSDAPL EEARQFAAQT VGNTYGNFSL 360
ATMFPRREFT REDYKRRLLD LELAPSASVV LLPAGRPATS IVHSSSGDIW TLLGTVLYPF 420
LAIWRLISNF LFSNPPPAQT SARATSTEPS NSASSSKSEK REPVRKRMLE KRGEDFKKEG 480
KIYRLRTQDD GEDENNTWNG NSTQQM 506 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
 GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW. 
Interpro
 IPR012336; Thioredoxin-like_fold.
 IPR001012; UBX. 
Pfam
 PF00789; UBX 
SMART
 SM00166; UBX 
PROSITE
 PS50033; UBX 
PRINTS