CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042757
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Beta-galactosidase-1-like protein 2 
Protein Synonyms/Alias
  
Gene Name
 GLB1L2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
25RDRLLKMKACGLNTLubiquitination[1]
104MRLRTTYKGFTEAVDubiquitination[2]
127RVVPLQYKRGGPIIAubiquitination[1]
155PAYMPYVKKALEDRGubiquitination[2]
173LLLTSDNKDGLSKGIubiquitination[2]
296EAGDYTAKYMKLRDFubiquitination[2]
441ENIDDQRKGLIGNLYubiquitination[1]
455YLNDSPLKNFRIYSLubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Glycosidase; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 575 AA 
Protein Sequence
XIFGGSIHYF RVPREYWRDR LLKMKACGLN TLTTYVPWNL HEPERGKFDF SGNLDLEAFV 60
LMAAEIGLWV ILRPGPYICS EMDLGGLPSW LLQDPGMRLR TTYKGFTEAV DLYFDHLMSR 120
VVPLQYKRGG PIIAVQVENE YGSYNKDPAY MPYVKKALED RGIVELLLTS DNKDGLSKGI 180
VQGVLATINL QSTHELQLLT TFLFNVQGTQ PKMVMEYWTG WFDSWGGPHN ILDSSEVLKT 240
VSAIVDAGSS INLYMFHGGT NFGFMNGAMH FHDYKSDVTS YDYDAVLTEA GDYTAKYMKL 300
RDFFGSISGI PLPPPPDLLP KMPYEPLTPV LYLSLWDALK YLGEPIKSEK PINMENLPVN 360
GGNGQSFGYI LYETSITSSG ILSGHVHDRG QVFVNTVSIG FLDYKTTKIA VPLIQGYTVL 420
RILVENRGRV NYGENIDDQR KGLIGNLYLN DSPLKNFRIY SLDMKKSFFQ RFGLDKWSSL 480
PETPTLPAFF LGSLSISSTP CDTFLKLEGW EKGVVFINGQ NLGRYWNIGP QKTLYLPGPW 540
LSSGINQVIV FEETMAGPAL QFTETPHLGR NQYIK 575 
Gene Ontology
 GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. 
Interpro
 IPR026283; B-gal_1-like.
 IPR008979; Galactose-bd-like.
 IPR019801; Glyco_hydro_35_CS.
 IPR013781; Glyco_hydro_catalytic_dom.
 IPR001944; Glycoside_Hdrlase_35.
 IPR017853; Glycoside_hydrolase_SF. 
Pfam
 PF01301; Glyco_hydro_35 
SMART
  
PROSITE
 PS01182; GLYCOSYL_HYDROL_F35 
PRINTS
 PR00742; GLHYDRLASE35.