CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028823
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ADP-sugar pyrophosphatase 
Protein Synonyms/Alias
  
Gene Name
 Nudt5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
13STESSPGKHLVTSEEacetylation[1]
26EELISEGKWVKFEKTubiquitination[2]
56KLTTRKGKSADAVSVacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 161 AA 
Protein Sequence
METRESTESS PGKHLVTSEE LISEGKWVKF EKTTYMDPTG KTRTWETVKL TTRKGKSADA 60
VSVIPVLQRT LHHECVILVK QFRPPMGSYC LEFPAGFIED GESPEAAALR ELEEETGYKG 120
EVAECSPAVC MDPGLSNCTT HVVTVTINGD DAGNVRPKPK P 161 
Gene Ontology
 GO:0019144; F:ADP-sugar diphosphatase activity; IEA:Compara.
 GO:0000287; F:magnesium ion binding; IEA:Compara.
 GO:0017110; F:nucleoside-diphosphatase activity; IDA:MGI.
 GO:0006139; P:nucleobase-containing compound metabolic process; IDA:MGI.
 GO:0009191; P:ribonucleoside diphosphate catabolic process; IEA:Compara. 
Interpro
 IPR020476; Nudix_hydrolase.
 IPR020084; NUDIX_hydrolase_CS.
 IPR000086; NUDIX_hydrolase_dom.
 IPR015797; NUDIX_hydrolase_dom-like. 
Pfam
 PF00293; NUDIX 
SMART
  
PROSITE
 PS51462; NUDIX
 PS00893; NUDIX_BOX 
PRINTS
 PR00502; NUDIXFAMILY.