CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041518
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UDP-glucose 6-dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 Ugdh 
Gene Synonyms/Alias
 rCG_57003 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
264MDQRIGNKFLKASVGacetylation[1]
370HLHIYDPKVPREQIVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; NAD; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 493 AA 
Protein Sequence
MVEIKKICCI GAGYVGGPTC SVIAHMCPEI RVTVVDVNEA RINAWNSPTL PIYEPGLKEV 60
VESCRGKNLF FSTNIDDAIR EADLVFISVN TPTKTYGMGK GRAADLKYIE ACARRIVQNS 120
NGYKIVTEKS TVPVRAAESI RRIFDANTKP NLNLQVLSNP EFLAEGTAIK DLKNPDRVLI 180
GGDETPEGQR AVQALCAVYE HWVPKEKILT TNTWSSELSK LAANAFLAQR ISSINSISAL 240
CEATGADVEE VATAIGMDQR IGNKFLKASV GFGGSCFQKD VLNLVYLCEA LNLPEVARYW 300
QQVIDMNDYQ RRRFASRIID SLFNTVTDKK IAILGFAFKK DTGDTRESSS IYISKYLMDE 360
GAHLHIYDPK VPREQIVVDL SHPGVSADDQ VSRLVTISKD PYEACDGAHA LVICTEWDMF 420
KELDYERIHK RMLKPAFIFD GRRVLDGLHN ELQTIGFQIE TIGKKVSSKR IPYTPGEIPK 480
FSLQDPPNKK PKV 493 
Gene Ontology
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0003979; F:UDP-glucose 6-dehydrogenase activity; IEA:EC.
 GO:0001702; P:gastrulation with mouth forming second; IEA:Compara. 
Interpro
 IPR008927; 6-PGluconate_DH_C-like.
 IPR016040; NAD(P)-bd_dom.
 IPR017476; Nucleotide_sugar_DH.
 IPR014027; UDP-Glc/GDP-Man_DH_C.
 IPR014026; UDP-Glc/GDP-Man_DH_dimer.
 IPR001732; UDP-Glc/GDP-Man_DH_N. 
Pfam
 PF00984; UDPG_MGDP_dh
 PF03720; UDPG_MGDP_dh_C
 PF03721; UDPG_MGDP_dh_N 
SMART
 SM00984; UDPG_MGDP_dh_C 
PROSITE
  
PRINTS